o-Phthalaldehyde
- CAS Number
- 643-79-8
- HSN Code
- 29122990
- Molecular Formula
- C8H6O2
- Catalogue Number
- AL02468
- Purity
- ≥99%
- Molecular Weight
- 134.14 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
o-Phthalaldehyde (AR, for fluorometry) is a widely used fluorogenic reagent for detecting primary amines and amino acids. It is particularly effective in HPLC fluorescence analysis due to its high reactivity with amines.
Also known as 1,2-Benzenedicarboxaldehyde.
- Catalogue No.
- AL02468
- CAS Number
- 643-79-8
- Molecular Formula
- C8H6O2
- Molecular Weight
- 134.14 g/mol
- HSN Code
- 29122990
- Grade
- AR, For Fluorometry
- Product Form
- Substance
White to pale yellow crystalline solid with a melting point of 50-52 °C and a boiling point of 300 °C. It is soluble in water and organic solvents such as ethanol and acetone.
- Appearance
- White to pale yellow crystalline solid
- Shelf Life
- 2 years
- Packaging
- 25 g in glass bottles
- Storage
- Store in a cool, dry place, away from light.
1.1 — Product identifier
- Chemical Name
- o-Phthalaldehyde
- Catalogue No.
- AL02468
- Product form
- Substance
- CAS Number
- 643-79-8
- EC Number
- 211-684-0
- Grade
- AR, For Fluorometry
- EC Index Number
- 605-005-00-2
- Chemical Formula
- C8H6O2
- HSN Code
- 29122990
- Synonyms
- 1,2-Benzenedicarboxaldehyde
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Fluorogenic reagent for detecting primary amines and amino acids.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Corrosive to metals; may cause skin and eye burns.
3.1 — Substance
- Name
- o-Phthalaldehyde
- CAS No.
- 643-79-8
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. Remove contaminated clothing. Seek medical attention if irritation persists.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Irritation of the respiratory tract, skin burns, eye damage.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes under fire conditions. Use water spray to cool containers.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area. Wear appropriate protective equipment. Contain spill and absorb with inert material.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Collect and dispose of in accordance with local regulations. Avoid release to the environment.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood. Wear gloves and eye protection. Avoid contact with skin and eyes.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials such as strong oxidizers.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White to pale yellow
- Odour
- Characteristic
- Odour threshold
- Not determined
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not determined
- Melting point
- 50-52 °C
- Freezing point
- Not determined
- Boiling point
- 300 °C
- Flash point
- Not determined
- Auto-ignition temperature
- Not determined
- Decomposition temperature
- Not determined
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- <0.1 mmHg at 25 °C
- Relative vapour density at 20°C
- Not determined
- Density
- 1.25 g/cm³
- Solubility
- Soluble in water and organic solvents
- Log Pow
- Not determined
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions. Reacts with strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Toxic if swallowed, inhaled, or absorbed through skin.
- Skin corrosion/irritation
- Causes skin burns.
- Serious eye damage/irritation
- Causes serious eye damage.
- Respiratory or skin sensitisation
- May cause allergic skin reaction.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- 2923
- UN-No. (IMDG)
- 2923
- UN-No. (IATA)
- 2923
- UN-No. (ADN)
- 2923
- UN-No. (RID)
- 2923
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- o-Phthalaldehyde
- Proper Shipping Name (IMDG)
- o-Phthalaldehyde
- Proper Shipping Name (IATA)
- o-Phthalaldehyde
- Proper Shipping Name (ADN)
- o-Phthalaldehyde
- Proper Shipping Name (RID)
- o-Phthalaldehyde
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 8 (6.1)
14.4 — Packing group
- Packing group (ADR)
- II
- Packing group (IMDG)
- II
- Packing group (IATA)
- II
- Packing group (ADN)
- II
- Packing group (RID)
- II
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as the key fluorogenic derivatization reagent for detecting primary amines and amino acids by HPLC fluorescence analysis. It is also utilized in various biochemical assays and research applications.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL02468
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 134.14 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | Pale yellow crystalline powder | Pale yellow crystalline powder |
| Assay | Min. 99% | 99.55% |
| Sulphated ash | <0.1% | <0.1% |
| Melting point | 53 – 56°C | 55°C |
The above product complies with AR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 99% AR | ≥99% | 50-52 °C | ≤0.5% | ≤0.1% | None detected | Soluble in water and organic solvents |
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