Osmium Tetroxide
- CAS Number
- 20816-12-0
- HSN Code
- 28439019
- Molecular Formula
- OsO4
- Catalogue Number
- AL1125A
- Purity
- ≥ 99.9%
- Molecular Weight
- 254.23 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Osmic acid (osmium tetroxide, AR) is a powerful and highly toxic oxidizing agent essential as a fixative and stain in electron microscopy.
Also known as Osmic acid.
- Catalogue No.
- AL1125A
- CAS Number
- 20816-12-0
- Molecular Formula
- OsO4
- Molecular Weight
- 254.23 g/mol
- HSN Code
- 28439019
- Grade
- AR (Analytical Reagent)
- Product Form
- Substance
Pale yellow to golden crystalline solid, extremely volatile; highly toxic vapor.
- Appearance
- Pale yellow to golden crystalline solid
- Shelf Life
- -
- Packaging
- -
- Storage
- Store at 2-8°C
1.1 — Product identifier
- Chemical Name
- Osmium Tetroxide
- Catalogue No.
- AL1125A
- Product form
- Substance
- CAS Number
- 20816-12-0
- EC Number
- 244-202-4
- Grade
- AR
- EC Index Number
- Not specified
- Chemical Formula
- OsO4
- HSN Code
- 28439019
- Synonyms
- Osmic acid
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Fixative and stain in electron microscopy
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Extremely toxic; may cause severe eye and respiratory tract damage.
3.1 — Substance
- Name
- Osmium Tetroxide
- CAS No.
- 20816-12-0
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air; seek medical attention immediately.
- First-aid measures after skin contact
- Wash with soap and water; seek medical attention if irritation occurs.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes; seek immediate medical attention.
- First-aid measures after ingestion
- Do not induce vomiting; seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Severe respiratory distress, eye damage, skin irritation.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Reacts violently with organic materials; use appropriate extinguishing media.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area; ventilate; use appropriate PPE.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Contain spill; use appropriate PPE; dispose of in accordance with local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood; wear appropriate PPE including gloves and goggles.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use NIOSH-approved respirator if exposure limits are exceeded.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- Pale yellow to golden
- Odour
- Odourless
- Odour threshold
- Not specified
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- -12.0 °C
- Freezing point
- Not specified
- Boiling point
- 130 °C
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- 0.5 mmHg at 20 °C
- Relative vapour density at 20°C
- Not specified
- Density
- 2.2 g/cm³
- Solubility
- Soluble in water, alcohol, and ether
- Log Pow
- Not specified
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Strong oxidizer
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Reacts violently with organic materials and reducing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong reducing agents, organic materials, and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 (oral, rat) 10 mg/kg; highly toxic.
- Skin corrosion/irritation
- Causes severe skin burns and eye damage.
- Serious eye damage/irritation
- Causes serious eye damage.
- Respiratory or skin sensitisation
- Not a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation and damage to organs.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2471
- UN-No. (IMDG)
- UN 2471
- UN-No. (IATA)
- UN 2471
- UN-No. (ADN)
- UN 2471
- UN-No. (RID)
- UN 2471
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Osmium Tetroxide
- Proper Shipping Name (IMDG)
- Osmium Tetroxide
- Proper Shipping Name (IATA)
- Osmium Tetroxide
- Proper Shipping Name (ADN)
- Osmium Tetroxide
- Proper Shipping Name (RID)
- Osmium Tetroxide
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as the standard fixative/stain for lipids and membranes in transmission electron microscopy sample preparation.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1125A
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 254.23 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 99.9% | 99.95% |
| Melting Point | -12.0 °C | -12.0 °C |
| Moisture Content | ≤ 0.5% | 0.3% |
| Residue on Ignition | ≤ 0.1% | 0.05% |
| Related Substances | None detected | None detected |
The above product is expected to comply with AR grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 99.9% AR | ≥ 99.9% | -12.0 °C (melting), 130 °C (boiling) | ≤ 0.5% | ≤ 0.1% | None detected | Soluble in water, alcohol, and ether |
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