Polyphosphoric Acid
- CAS Number
- 8017-16-1
- HSN Code
- 28092020
- Molecular Formula
- Hn+2PnO3n+1
- Catalogue Number
- AL2480B
- Purity
- ≥ 85%
- Molecular Weight
- Polymer g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Polyphosphoric acid (for synthesis, teraphosphoric acid) is a condensed phosphoric acid that serves as a powerful dehydrating and cyclization agent in organic synthesis. It is particularly notable for its ability to facilitate the formation of heterocycles and other complex organic structures. This compound is characterized by its high viscosity and ability to act as a medium for various chemical reactions. With a CAS number of 8017-16-1, it is widely utilized in the pharmaceutical and chemical industries for its unique reactivity and effectiveness in synthesis processes.
Also known as Teraphosphoric Acid.
- Catalogue No.
- AL2480B
- CAS Number
- 8017-16-1
- Molecular Formula
- Hn+2PnO3n+1
- Molecular Weight
- Polymer g/mol
- HSN Code
- 28092020
- Grade
- For Synthesis
- Product Form
- Substance
Polyphosphoric acid appears as a colorless to pale yellow viscous liquid. It has a density of approximately 1.7 g/cm³, which contributes to its thick consistency. The boiling point of polyphosphoric acid is around 300 °C, and it is soluble in water, forming a highly acidic solution. The pH of a concentrated solution can be significantly below 1, indicating its strong acidic nature. It does not have a defined melting point due to its polymeric nature, but it can solidify at lower temperatures.
- Appearance
- Colorless to pale yellow viscous liquid
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place away from incompatible materials.
1.1 — Product identifier
- Chemical Name
- Polyphosphoric Acid
- Catalogue No.
- AL2480B
- Product form
- Substance
- CAS Number
- 8017-16-1
- EC Number
- Not specified
- Grade
- For Synthesis
- EC Index Number
- Not specified
- Chemical Formula
- Hn+2PnO3n+1
- HSN Code
- 28092020
- Synonyms
- Teraphosphoric Acid
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Dehydrating and cyclization agent in organic synthesis
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Corrosive to metals; may cause severe skin burns and eye damage.
3.1 — Substance
- Name
- Polyphosphoric Acid
- CAS No.
- 8017-16-1
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention.
- First-aid measures after skin contact
- Wash skin thoroughly with soap and water. Remove contaminated clothing. Seek medical attention if irritation persists.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Burning sensation, respiratory distress, skin irritation, and eye damage.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes under fire conditions. Use water spray to cool containers.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and absorb with inert material. Dispose of in accordance with local regulations.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Neutralize with a suitable alkaline material and absorb with inert material.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use personal protective equipment. Avoid contact with skin and eyes. Ensure adequate ventilation.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in tightly closed containers in a cool, dry place, away from incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless to pale yellow
- Odour
- Odourless
- Odour threshold
- Not specified
- pH value
- <1 (concentrated solution)
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- Not applicable
- Freezing point
- Not applicable
- Boiling point
- ~300 °C
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not specified
- Relative vapour density at 20°C
- Not specified
- Density
- ~1.7 g/cm³
- Solubility
- Soluble in water
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Reacts violently with water and strong bases, releasing heat and forming phosphoric acid.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong bases, strong oxidizers, and water.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Not classified as acutely toxic, but can cause severe burns.
- Skin corrosion/irritation
- Causes severe skin burns.
- Serious eye damage/irritation
- Causes serious eye damage.
- Respiratory or skin sensitisation
- Not a skin sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 3264
- UN-No. (IMDG)
- UN 3264
- UN-No. (IATA)
- UN 3264
- UN-No. (ADN)
- UN 3264
- UN-No. (RID)
- UN 3264
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Polyphosphoric Acid
- Proper Shipping Name (IMDG)
- Polyphosphoric Acid
- Proper Shipping Name (IATA)
- Polyphosphoric Acid
- Proper Shipping Name (ADN)
- Polyphosphoric Acid
- Proper Shipping Name (RID)
- Polyphosphoric Acid
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 8 (Corrosive)
14.4 — Packing group
- Packing group (ADR)
- II
- Packing group (IMDG)
- II
- Packing group (IATA)
- II
- Packing group (ADN)
- II
- Packing group (RID)
- II
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Polyphosphoric acid is primarily used as a dehydrating and cyclization reagent in organic synthesis, particularly in the production of heterocycles and pharmaceuticals. One of its notable applications is in the Bischler-Napieralski reaction, which is essential for synthesizing various alkaloids and other complex organic molecules. Additionally, it is employed in the preparation of phosphonates and phosphonamides, which are important in agrochemicals and pharmaceuticals. Its ability to facilitate the removal of water makes it valuable in polymer chemistry and the production of phosphoric esters.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL2480B
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- Polymer g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | Colorless viscous liquid | Colorless viscous liquid |
| Assay (by acidimetric, as P2O5) | About 85.0% | 85.69% |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For Synthesis | ≥ 85% | ~300 °C | ≤ 5% | ≤ 1% | None detected | Soluble in water |
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