Propylene Glycol

AR (Analytical Reagent) For Laboratory Use
CAS Number
57-55-6
HSN Code
29053200
Molecular Formula
C3H8O2
Catalogue Number
AL1275A
Purity
99.5%
Molecular Weight
76.10 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance Colorless viscous liquid
Shelf Life -
Packaging -
Storage Store in a cool, dry place away from direct sunlight.

Propylene Glycol 99.5% AR is a high-purity, analytical-grade solvent and humectant, widely recognized for its versatility in various applications. With a molecular formula of C3H8O2 and a molecular weight of 76.10 g/mol, this compound is notable for its low toxicity and excellent solubility properties. It is commonly used in laboratories for precise analytical work due to its stringent purity standards, ensuring reliable results in sensitive applications. This product is particularly valued in the pharmaceutical and cosmetic industries for its role in formulation research and development.

Also known as 1,2-Propanediol, Propylene glycol.

Catalogue No.
AL1275A
CAS Number
57-55-6
Molecular Formula
C3H8O2
Molecular Weight
76.10 g/mol
HSN Code
29053200
Grade
AR (Analytical Reagent)
Product Form
Substance

Propylene Glycol 99.5% AR is a colorless, viscous liquid with a density of 1.036 g/mL at 20°C. It has a boiling point of approximately 188.2°C and a melting point of -59°C, making it stable across a wide range of temperatures. The compound is hygroscopic, readily absorbing moisture from the air, and is miscible with water, acetone, and chloroform. It has a low vapor pressure of 0.1 mmHg at 20°C, indicating a low tendency to evaporate. The liquid has a faint, sweet odor and a pH value of around 6-7, making it suitable for various applications without significant reactivity.

Appearance
Colorless viscous liquid
Shelf Life
-
Packaging
-
Storage
Store in a cool, dry place away from direct sunlight.

1.1 — Product identifier

Chemical Name
Propylene Glycol
Catalogue No.
AL1275A
Product form
Substance
CAS Number
57-55-6
EC Number
200-338-0
Grade
AR
EC Index Number
603-033-00-0
Chemical Formula
C3H8O2
HSN Code
29053200
Synonyms
1,2-Propanediol, Propylene glycol

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used as a solvent and humectant in pharmaceuticals and cosmetics.
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
None identified.

3.1 — Substance

Name
Propylene Glycol
CAS No.
57-55-6

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
May cause mild irritation to skin and eyes.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Combustible liquid. Use appropriate fire-fighting measures.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and absorb with inert material. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Use appropriate protective equipment. Clean up spills immediately to prevent slipping hazards.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place, away from incompatible materials.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Not required under normal conditions of use.

9.1 — Information on basic physical and chemical properties

Physical state
Liquid
Colour
Colorless
Odour
Faint, sweet
Odour threshold
Not specified
pH value
6-7
Relative evaporation rate (butylacetate=1)
<1
Melting point
-59°C
Freezing point
Not specified
Boiling point
188.2°C
Flash point
99°C
Auto-ignition temperature
Not specified
Decomposition temperature
Not specified
Flammability (solid, gas)
Not applicable
Vapour pressure
0.1 mmHg at 20°C
Relative vapour density at 20°C
>1
Density
1.036 g/mL
Solubility
Miscible with water, acetone, and chloroform
Log Pow
-0.92
Viscosity, kinematic
Not specified
Viscosity, dynamic
Not specified
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not specified

10.1 — Reactivity

Reactivity
Stable under normal conditions.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizing agents.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
LD50 (oral, rat) > 20,000 mg/kg.
Skin corrosion/irritation
Mild irritant.
Serious eye damage/irritation
Mild irritant.
Respiratory or skin sensitisation
Not a sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
Not classified as a specific target organ toxicant.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
Not assigned
UN-No. (IMDG)
Not assigned
UN-No. (IATA)
Not assigned
UN-No. (ADN)
Not assigned
UN-No. (RID)
Not assigned

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Not classified as dangerous goods
Proper Shipping Name (IMDG)
Not classified as dangerous goods
Proper Shipping Name (IATA)
Not classified as dangerous goods
Proper Shipping Name (ADN)
Not classified as dangerous goods
Proper Shipping Name (RID)
Not classified as dangerous goods

14.3 — Transport hazard class(es)

Transport hazard class(es)
Not applicable

14.4 — Packing group

Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Propylene Glycol 99.5% AR is extensively used as a humectant and solvent in the pharmaceutical industry, particularly in the formulation of oral, topical, and injectable medications. Its low toxicity profile makes it an ideal choice for cosmetic formulations, where it serves to retain moisture and enhance texture. Additionally, it is utilized in food processing as a food additive (E1520) and in the production of antifreeze and de-icing solutions. The compound is also employed in the manufacture of plastics, resins, and as a carrier for flavors and fragrances in various consumer products.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL1275A
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
76.10 g/mol
Test Standard Observed
Assay 99.5% min 99.7%
Density 1.036 g/mL 1.036 g/mL
pH 6-7 6.5
Moisture Content <0.1% 0.05%
Residue on Ignition <0.01% <0.005%
Related Substances None detected None detected

The above product is expected to comply with AR grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
AR 99.5% -59°C / 188.2°C <0.1% <0.01% None detected Miscible with water
View full Technical Data Sheet

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