Semicarbazide Hydrochloride
- CAS Number
- 563-41-7
- HSN Code
- 29280090
- Molecular Formula
- CH5N3O·HCl
- Catalogue Number
- AL01310
- Purity
- 99.5%
- Molecular Weight
- 111.53 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Semicarbazide hydrochloride is a white crystalline compound that serves as an important reagent in organic chemistry, particularly in the derivatization of carbonyl compounds such as aldehydes and ketones. This AR-grade product is characterized by its high purity of 99.5%, making it suitable for precise analytical applications. The compound is a hydrochloride salt of semicarbazide, which is a derivative of urea and is known for its ability to form stable derivatives with carbonyl groups. Its CAS number is 563-41-7, and it is classified under the HS Code 29280090, indicating its chemical nature and regulatory status.
Also known as Semicarbazide Hydrochloride, Semicarbazide HCl.
- Catalogue No.
- AL01310
- CAS Number
- 563-41-7
- Molecular Formula
- CH5N3O·HCl
- Molecular Weight
- 111.53 g/mol
- HSN Code
- 29280090
- Grade
- AR (Analytical Reagent)
- Product Form
- Substance
Semicarbazide hydrochloride appears as a white crystalline powder. It has a melting point of approximately 165-170 °C and is highly soluble in water, allowing for easy preparation of solutions for analytical use. The compound has a density of about 1.25 g/cm³. It is odorless and non-volatile, which is advantageous in laboratory settings where odor control is important. The compound is stable under normal conditions but should be stored in a cool, dry place to maintain its integrity.
- Appearance
- White crystalline powder
- Shelf Life
- 2 years
- Packaging
- Available in 100 g and 500 g bottles
- Storage
- Store in a cool, dry place, away from light.
1.1 — Product identifier
- Chemical Name
- Semicarbazide Hydrochloride
- Catalogue No.
- AL01310
- Product form
- Substance
- CAS Number
- 563-41-7
- EC Number
- 209-812-0
- Grade
- AR
- EC Index Number
- 612-005-00-0
- Chemical Formula
- CH5N3O·HCl
- HSN Code
- 29280090
- Synonyms
- Semicarbazide Hydrochloride, Semicarbazide HCl
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Analytical reagent for derivatization of carbonyl compounds
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Toxic if swallowed, inhaled, or in contact with skin.
3.1 — Substance
- Name
- Semicarbazide Hydrochloride
- CAS No.
- 563-41-7
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention if irritation persists.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Symptoms of exposure may include headache, dizziness, nausea, and respiratory distress.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Toxic fumes may be released in a fire. Use appropriate fire-fighting measures.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Wear appropriate protective equipment. Contain spill and collect for disposal.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use inert absorbent material to collect the spill. Dispose of in accordance with local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use personal protective equipment as required. Work in a well-ventilated area.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a tightly closed container in a cool, dry place.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 165-170 °C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.25 g/cm³
- Solubility
- Soluble in water
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions, but may react with strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids, and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Toxic if swallowed, inhaled, or absorbed through the skin.
- Skin corrosion/irritation
- May cause skin irritation.
- Serious eye damage/irritation
- Causes serious eye irritation.
- Respiratory or skin sensitisation
- May cause allergic skin reaction.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2811
- UN-No. (IMDG)
- UN 2811
- UN-No. (IATA)
- UN 2811
- UN-No. (ADN)
- UN 2811
- UN-No. (RID)
- UN 2811
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (IMDG)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (IATA)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (ADN)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (RID)
- Toxic solid, organic, n.o.s.
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- III
- Packing group (IMDG)
- III
- Packing group (IATA)
- III
- Packing group (ADN)
- III
- Packing group (RID)
- III
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Semicarbazide hydrochloride is primarily used as a derivatizing agent in analytical chemistry, particularly for the identification and quantification of aldehydes and ketones through the formation of semicarbazones. This reaction is crucial in various fields, including pharmaceuticals, environmental analysis, and food safety testing. Additionally, it is utilized in the synthesis of other chemical compounds and in research settings where precise measurement of carbonyl compounds is required. Its applications extend to the study of metabolic pathways in biochemistry and the development of new analytical methods.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL01310
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 111.53 g/mol
| Test | Standard | Observed |
|---|---|---|
| Purity | 99.5% min | 99.7% |
| Melting Point | 165-170 °C | 168 °C |
| Moisture Content | <0.5% | 0.3% |
| Residue on Ignition | <0.1% | 0.05% |
| Related Substances | None detected | None detected |
The above product is expected to comply with AR grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| AR | 99.5% | 165-170 °C | <0.5% | <0.1% | None detected | Soluble in water |
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