Silica Gel
- CAS Number
- 112926-00-8
- HSN Code
- 28112200
- Molecular Formula
- SiO2
- Catalogue Number
- AL01319
- Purity
- ≥ 99%
- Molecular Weight
- 60.08 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Silica gel ‘H’ for TLC (without binder) is a high-purity, binder-free stationary phase specifically designed for thin-layer chromatography (TLC). This product is notable for its ability to provide a more fragile and delicate TLC plate, which is essential for certain chromatographic applications where traditional binder-containing silica may interfere with the separation process. The absence of a binder allows for improved resolution and sensitivity in the analysis of complex mixtures. Silica gel is widely recognized for its high surface area and porosity, making it an ideal choice for various analytical and preparative chromatography techniques.
Also known as Silica, Silicon Dioxide.
- Catalogue No.
- AL01319
- CAS Number
- 112926-00-8
- Molecular Formula
- SiO2
- Molecular Weight
- 60.08 g/mol
- HSN Code
- 28112200
- Grade
- For TLC, without binder
- Product Form
- Substance
Silica gel ‘H’ for TLC appears as a white fine powder, characterized by its high purity and uniform particle size. It has a typical bulk density of approximately 0.5 g/cm³ and a specific surface area of around 300 m²/g. The material is insoluble in water and most organic solvents, making it suitable for a wide range of solvent systems used in TLC. The melting point of silica is approximately 1710 °C, and it does not have a defined boiling point as it sublimates at high temperatures. The powder is odorless and non-hygroscopic, ensuring stability during storage and use.
- Appearance
- White fine powder
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place away from direct sunlight.
1.1 — Product identifier
- Chemical Name
- Silica Gel
- Catalogue No.
- AL01319
- Product form
- Substance
- CAS Number
- 112926-00-8
- EC Number
- 238-878-4
- Grade
- For TLC, without binder
- EC Index Number
- Silica gel is not classified under the EC Index Number.
- Chemical Formula
- SiO2
- HSN Code
- 28112200
- Synonyms
- Silica, Silicon Dioxide
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used as a stationary phase in thin-layer chromatography (TLC).
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- May cause respiratory irritation if inhaled.
3.1 — Substance
- Name
- Silica Gel
- CAS No.
- 112926-00-8
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. If symptoms occur, seek medical attention.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Coughing, sneezing, or respiratory discomfort upon inhalation.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Non-flammable; however, silica gel can produce dust that may be a respiratory hazard.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Avoid dust formation. Use appropriate personal protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Collect spillage and dispose of in accordance with local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid creating dust. Use appropriate personal protective equipment, including dust masks and gloves.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, in a tightly closed container.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use a dust mask or respirator if dust is generated.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 1710 °C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Non-flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 0.5 g/cm³
- Solubility
- Insoluble in water and organic solvents
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not applicable
- Oxidising properties
- Not applicable
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong acids and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Not classified as toxic.
- Skin corrosion/irritation
- Not classified as an irritant.
- Serious eye damage/irritation
- May cause mild irritation.
- Respiratory or skin sensitisation
- Not a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not assigned
- UN-No. (IMDG)
- Not assigned
- UN-No. (IATA)
- Not assigned
- UN-No. (ADN)
- Not assigned
- UN-No. (RID)
- Not assigned
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not classified as dangerous goods
- Proper Shipping Name (IMDG)
- Not classified as dangerous goods
- Proper Shipping Name (IATA)
- Not classified as dangerous goods
- Proper Shipping Name (ADN)
- Not classified as dangerous goods
- Proper Shipping Name (RID)
- Not classified as dangerous goods
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Silica gel ‘H’ for TLC is primarily used in the preparation of binder-free TLC plates, which are essential for specific chromatographic separation applications. It is widely utilized in the pharmaceutical industry for the analysis of drug compounds, in environmental testing for the separation of pollutants, and in food safety for the analysis of additives and contaminants. Additionally, this silica gel is employed in academic research laboratories for various analytical purposes, including the separation of natural products and the analysis of complex mixtures in organic chemistry.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL01319
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 60.08 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay Purity | ≥ 99% | 99.5% |
| Moisture Content | ≤ 1% | 0.5% |
| Residue on Ignition | ≤ 0.5% | 0.3% |
| Particle Size Distribution | D90 < 20 µm | D90 = 15 µm |
| pH in water | Not applicable | Not applicable |
The above product is expected to comply with For TLC, without binder grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For TLC, without binder | ≥ 99% | 1710 °C | ≤ 1% | ≤ 0.5% | None detected | Insoluble in water and organic solvents |
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