Silica Gel GF 254
- CAS Number
- 112926-00-8
- HSN Code
- 28112200
- Molecular Formula
- SiO2
- Catalogue Number
- AL01318
- Purity
- ≥ 95%
- Molecular Weight
- 60.08 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Silica gel GF 254 for TLC (with binder) is a specialized adsorbent used in thin-layer chromatography (TLC) that incorporates a fluorescent indicator. This unique feature allows for the visualization of UV-absorbing compounds when exposed to ultraviolet light at 254 nm. The product is composed of silica dioxide (SiO2) combined with a gypsum binder, enhancing its structural integrity and usability in laboratory settings. Silica gel GF 254 is widely recognized for its effectiveness in separating and analyzing organic compounds, making it an essential tool in various analytical chemistry applications.
Also known as Silica gel, Silica gel with binder.
- Catalogue No.
- AL01318
- CAS Number
- 112926-00-8
- Molecular Formula
- SiO2
- Molecular Weight
- 60.08 g/mol
- HSN Code
- 28112200
- Grade
- For TLC, with binder
- Product Form
- Substance
Silica gel GF 254 appears as a white fine powder, characterized by its high surface area and porosity. It has a density of approximately 0.5-0.7 g/cm³, which contributes to its effectiveness as an adsorbent. The material is insoluble in water and most organic solvents, making it stable under a variety of conditions. The melting point of silica is around 1710 °C, and it does not have a defined boiling point as it sublimates at high temperatures. The product is non-flammable and does not pose significant hazards under normal handling conditions.
- Appearance
- White fine powder
- Shelf Life
- -
- Packaging
- Typically packaged in airtight containers to prevent moisture absorption
- Storage
- Store in a cool, dry place away from direct sunlight and moisture.
1.1 — Product identifier
- Chemical Name
- Silica Gel GF 254
- Catalogue No.
- AL01318
- Product form
- Substance
- CAS Number
- 112926-00-8
- EC Number
- None
- Grade
- For TLC, with binder
- EC Index Number
- None
- Chemical Formula
- SiO2
- HSN Code
- 28112200
- Synonyms
- Silica gel, Silica gel with binder
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Adsorbent for thin-layer chromatography
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Dust may cause respiratory irritation
3.1 — Substance
- Name
- Silica Gel GF 254
- CAS No.
- 112926-00-8
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Irritation of the respiratory tract, skin, and eyes upon exposure to dust.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Non-flammable; however, dust may pose a fire hazard in certain conditions.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Avoid dust generation. Use appropriate personal protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Collect material using a vacuum or wet sweeping method to minimize dust generation.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use appropriate personal protective equipment, including dust masks and gloves, to minimize exposure.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use a dust mask or respirator if dust is generated.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 1710 °C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Non-flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 0.5-0.7 g/cm³
- Solubility
- Insoluble in water and organic solvents
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not applicable
- Oxidising properties
- Not applicable
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid contact with strong acids and bases.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong acids and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Not classified as acutely toxic.
- Skin corrosion/irritation
- May cause mild irritation upon prolonged contact.
- Serious eye damage/irritation
- May cause mechanical irritation to eyes.
- Respiratory or skin sensitisation
- Not a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not applicable
- UN-No. (IMDG)
- Not applicable
- UN-No. (IATA)
- Not applicable
- UN-No. (ADN)
- Not applicable
- UN-No. (RID)
- Not applicable
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not classified as dangerous goods
- Proper Shipping Name (IMDG)
- Not classified as dangerous goods
- Proper Shipping Name (IATA)
- Not classified as dangerous goods
- Proper Shipping Name (ADN)
- Not classified as dangerous goods
- Proper Shipping Name (RID)
- Not classified as dangerous goods
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Silica gel GF 254 is primarily used in the preparation of TLC plates, which are essential for the separation and identification of organic compounds in various fields such as pharmaceuticals, environmental analysis, and food safety. The fluorescent indicator allows for easy detection of compounds that absorb UV light, facilitating qualitative and quantitative analysis. Additionally, this product is utilized in research laboratories for method development and optimization in chromatography, as well as in educational settings for teaching chromatography techniques.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL01318
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 60.08 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay Purity | ≥ 95% | 96.5% |
| Moisture Content | ≤ 5% | 3.2% |
| Residue on Ignition | ≤ 1% | 0.5% |
| Related Substances | None | None Detected |
| Solubility | Insoluble in water and organic solvents | Confirmed |
The above product is expected to comply with For TLC, with binder grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For TLC, with binder | ≥ 95% | 1710 °C | ≤ 5% | ≤ 1% | None | Insoluble in water and organic solvents |
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