Silica Gel HF 254

For TLC, without binder For Laboratory Use
CAS Number
112926-00-8
HSN Code
28112200
Molecular Formula
SiO2
Catalogue Number
AL01320
Purity
>99%
Molecular Weight
60.08 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White fine powder
Shelf Life -
Packaging Available in various packaging options, typically in airtight containers to prevent contamination.
Storage Store in a cool, dry place away from direct sunlight and moisture.

Silica gel HF 254 for TLC (without binder) is a specialized form of silica gel designed for thin-layer chromatography (TLC). This product features a binder-free formulation, which enhances its performance in chromatographic applications. The inclusion of a fluorescent UV indicator allows for the visualization of compounds under UV light, making it particularly useful for detecting UV-active substances. With a CAS number of 112926-00-8, this silica gel is widely utilized in laboratories for analytical and preparative purposes, ensuring high resolution and sensitivity in separation processes.

Also known as Fluorescent Silica Gel, Silica Gel for TLC.

Catalogue No.
AL01320
CAS Number
112926-00-8
Molecular Formula
SiO2
Molecular Weight
60.08 g/mol
HSN Code
28112200
Grade
For TLC, without binder
Product Form
Substance

Silica gel HF 254 appears as a white fine powder, characterized by its high surface area and porosity. It has a typical particle size range of 5-20 micrometers, which is optimal for TLC applications. The material is insoluble in water and organic solvents, making it stable under various conditions. The bulk density of silica gel HF 254 is approximately 0.5-0.7 g/cm³, and it has a high thermal stability, with a decomposition temperature exceeding 600 °C. The product is non-hygroscopic, ensuring consistent performance without moisture interference.

Appearance
White fine powder
Shelf Life
-
Packaging
Available in various packaging options, typically in airtight containers to prevent contamination.
Storage
Store in a cool, dry place away from direct sunlight and moisture.

1.1 — Product identifier

Chemical Name
Silica Gel HF 254
Catalogue No.
AL01320
Product form
Substance
CAS Number
112926-00-8
EC Number
None
Grade
For TLC, without binder
EC Index Number
None
Chemical Formula
SiO2
HSN Code
28112200
Synonyms
Fluorescent Silica Gel, Silica Gel for TLC

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used as a stationary phase in thin-layer chromatography (TLC)
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
May cause respiratory irritation if inhaled; avoid dust generation.

3.1 — Substance

Name
Silica Gel HF 254
CAS No.
112926-00-8

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. If irritation persists, seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. If symptoms occur, seek medical attention.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
Irritation of the respiratory tract, skin, and eyes.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Non-flammable; however, silica gel can produce irritating dust when heated.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Avoid dust generation. Use appropriate personal protective equipment. Ensure adequate ventilation.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Collect material using a vacuum or wet sweeping method. Dispose of in accordance with local regulations.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Avoid inhalation of dust. Use appropriate personal protective equipment such as gloves and masks when handling.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place in a tightly sealed container.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use a dust mask or respirator if dust is generated.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White
Odour
Odourless
Odour threshold
Not applicable
pH value
Not applicable
Relative evaporation rate (butylacetate=1)
Not applicable
Melting point
Not applicable
Freezing point
Not applicable
Boiling point
Not applicable
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
>600 °C
Flammability (solid, gas)
Non-flammable
Vapour pressure
Not applicable
Relative vapour density at 20°C
Not applicable
Density
0.5-0.7 g/cm³
Solubility
Insoluble in water and organic solvents
Log Pow
Not applicable
Viscosity, kinematic
Not applicable
Viscosity, dynamic
Not applicable
Explosive properties
Not applicable
Oxidising properties
Not applicable
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Stable under normal conditions; avoid contact with strong acids or bases.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong acids and bases.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Not classified as acutely toxic; however, inhalation of dust may cause respiratory irritation.
Skin corrosion/irritation
May cause mild skin irritation.
Serious eye damage/irritation
May cause mild eye irritation.
Respiratory or skin sensitisation
Not a skin sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
No specific target organ toxicity identified.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
Not classified as dangerous goods.
UN-No. (IMDG)
Not classified as dangerous goods.
UN-No. (IATA)
Not classified as dangerous goods.
UN-No. (ADN)
Not classified as dangerous goods.
UN-No. (RID)
Not classified as dangerous goods.

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Not applicable
Proper Shipping Name (IMDG)
Not applicable
Proper Shipping Name (IATA)
Not applicable
Proper Shipping Name (ADN)
Not applicable
Proper Shipping Name (RID)
Not applicable

14.3 — Transport hazard class(es)

Transport hazard class(es)
Not applicable

14.4 — Packing group

Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Silica gel HF 254 is primarily used in the preparation of binder-free TLC plates, which are essential for the separation and analysis of organic compounds. Its fluorescent properties enable the detection of UV-active compounds, making it invaluable in pharmaceutical, environmental, and biochemical research. This silica gel is also employed in the purification of natural products and in the analysis of food and beverage samples. Additionally, it serves as a stationary phase in various chromatographic techniques, enhancing the resolution and efficiency of separations.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL01320
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
60.08 g/mol
Test Standard Observed
Assay Purity >99% 99.5%
Moisture Content <1% 0.5%
Residue on Ignition <0.5% 0.3%
Particle Size Distribution 5-20 micrometers 15 micrometers
pH Value Not applicable Not applicable

The above product is expected to comply with For TLC, without binder grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
For TLC, without binder >99% Not applicable <1% <0.5% None detected Insoluble in water
View full Technical Data Sheet

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