Sodium Bicarbonate
- CAS Number
- 144-55-8
- HSN Code
- 28363000
- Molecular Formula
- NaHCO3
- Catalogue Number
- AL1352C
- Purity
- 99.7%
- Molecular Weight
- 84.01 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Sodium bicarbonate, also known as sodium hydrogen carbonate, is a white crystalline powder that serves as a vital component in various biochemical applications. With a high purity of 99.7%, this molecular-biology-grade sodium bicarbonate is specifically purified for use in cell-culture media formulation. It plays a crucial role in maintaining pH stability in biological systems, making it essential for research in molecular biology and cell culture. Its CAS number is 144-55-8, and it is recognized for its non-hazardous nature, making it safe for laboratory use.
Also known as Baking soda, Sodium hydrogen carbonate.
- Catalogue No.
- AL1352C
- CAS Number
- 144-55-8
- Molecular Formula
- NaHCO3
- Molecular Weight
- 84.01 g/mol
- HSN Code
- 28363000
- Grade
- For Molecular Biology
- Product Form
- Substance
Sodium bicarbonate appears as a white crystalline powder with a characteristic mild alkaline taste. It is highly soluble in water, with a solubility of approximately 96 g/L at 20°C. The melting point of sodium bicarbonate is around 50°C, where it decomposes rather than melting, releasing carbon dioxide and water. The density of sodium bicarbonate is approximately 2.20 g/cm³. It has a pH of about 8.4 in a 1% aqueous solution, indicating its mild alkalinity, which is beneficial for buffering applications.
- Appearance
- White crystalline powder
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place away from incompatible materials.
1.1 — Product identifier
- Chemical Name
- Sodium Bicarbonate
- Catalogue No.
- AL1352C
- Product form
- Substance
- CAS Number
- 144-55-8
- EC Number
- 205-633-8
- Grade
- For Molecular Biology
- EC Index Number
- No data available
- Chemical Formula
- NaHCO3
- HSN Code
- 28363000
- Synonyms
- Baking soda, Sodium hydrogen carbonate
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Buffering agent in cell culture media
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- None known
3.1 — Substance
- Name
- Sodium Bicarbonate
- CAS No.
- 144-55-8
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- No significant symptoms expected under normal use.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Non-flammable; may release carbon dioxide when heated.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and collect for disposal. Avoid dust generation.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid dust formation. Use in a well-ventilated area.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials such as strong acids.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Not required under normal conditions of use.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- 8.4 (1% solution)
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- Decomposes at 50°C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- 50°C
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 2.20 g/cm³
- Solubility
- 96 g/L in water at 20°C
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; reacts with acids to produce carbon dioxide.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong acids, strong bases, and reactive metals.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Not classified as toxic.
- Skin corrosion/irritation
- Not classified as an irritant.
- Serious eye damage/irritation
- Not classified as an irritant.
- Respiratory or skin sensitisation
- Not a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not assigned
- UN-No. (IMDG)
- Not assigned
- UN-No. (IATA)
- Not assigned
- UN-No. (ADN)
- Not assigned
- UN-No. (RID)
- Not assigned
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Sodium Bicarbonate
- Proper Shipping Name (IMDG)
- Sodium Bicarbonate
- Proper Shipping Name (IATA)
- Sodium Bicarbonate
- Proper Shipping Name (ADN)
- Sodium Bicarbonate
- Proper Shipping Name (RID)
- Sodium Bicarbonate
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not hazardous
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Sodium bicarbonate is widely used in molecular biology as a pH-buffering agent, particularly in cell-culture media formulations. It is integral to the bicarbonate/CO2 buffering system, which helps maintain physiological pH levels in cell cultures. Additionally, it is utilized in various laboratory applications, including as a reagent in biochemical assays and as a component in buffer solutions. Beyond molecular biology, sodium bicarbonate finds applications in the food industry as a leavening agent, in pharmaceuticals for antacid formulations, and in environmental applications for neutralizing acidic soils.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1352C
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 84.01 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 99.7% min | 99.8% |
| Moisture Content | <0.5% | 0.3% |
| Residue on Ignition | <0.1% | 0.05% |
| pH (1% solution) | 8.4 | 8.4 |
| Solubility | 96 g/L in water at 20°C | 96 g/L |
The above product is expected to comply with For Molecular Biology grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For Molecular Biology | 99.7% | Decomposes at 50°C | <0.5% | <0.1% | None detected | 96 g/L in water at 20°C |
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