Sodium Hydroxide

For Molecular Biology For Laboratory Use
CAS Number
1310-73-2
HSN Code
28151190
Molecular Formula
NaOH
Catalogue Number
AL1383A
Purity
98%
Molecular Weight
40.00 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White pellets
Shelf Life -
Packaging Available in various packaging options, typically in sealed containers to prevent moisture absorption.
Storage Store in a cool, dry place, away from incompatible materials such as acids and organic compounds.

Sodium hydroxide (NaOH), commonly known as caustic soda, is a highly versatile and widely used inorganic compound. This specific grade of sodium hydroxide is purified for molecular biology applications, particularly in DNA extraction and RNA denaturation protocols. With a purity of 98%, it is suitable for sensitive biological experiments where contamination must be minimized. Its strong alkaline properties make it essential in various biochemical processes, ensuring optimal conditions for molecular biology research.

Also known as Caustic Soda, Lye.

Catalogue No.
AL1383A
CAS Number
1310-73-2
Molecular Formula
NaOH
Molecular Weight
40.00 g/mol
HSN Code
28151190
Grade
For Molecular Biology
Product Form
Substance

Sodium hydroxide appears as white, hygroscopic pellets that readily absorb moisture from the air. It has a melting point of 318 °C and a boiling point of 1380 °C. The density of sodium hydroxide is approximately 2.13 g/cm³. It is highly soluble in water, with a solubility of about 111 g/100 mL at 20 °C, producing a strongly alkaline solution. The pH of a 1 M solution is around 13, indicating its strong basicity.

Appearance
White pellets
Shelf Life
-
Packaging
Available in various packaging options, typically in sealed containers to prevent moisture absorption.
Storage
Store in a cool, dry place, away from incompatible materials such as acids and organic compounds.

1.1 — Product identifier

Chemical Name
Sodium Hydroxide
Catalogue No.
AL1383A
Product form
Substance
CAS Number
1310-73-2
EC Number
215-185-5
Grade
For Molecular Biology
EC Index Number
NaOH
Chemical Formula
NaOH
HSN Code
28151190
Synonyms
Caustic Soda, Lye

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used in molecular biology for DNA extraction and RNA denaturation.
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
Corrosive to metals; may cause severe burns to skin and eyes.

3.1 — Substance

Name
Sodium Hydroxide
CAS No.
1310-73-2

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash skin thoroughly with soap and water. Seek medical attention if irritation develops.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do NOT induce vomiting. Seek medical attention immediately.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
Burning sensation, redness, and pain in contact areas; respiratory distress if inhaled.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Non-flammable, but may react with water to produce heat and caustic solutions.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and neutralize with dilute acid. Wear appropriate protective equipment.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Collect and dispose of in accordance with local regulations.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Use personal protective equipment such as gloves and goggles. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a tightly closed container in a cool, dry place, away from incompatible materials.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use appropriate respiratory protection if dust or mist is generated.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White
Odour
Odourless
Odour threshold
Not applicable
pH value
13 (1 M solution)
Relative evaporation rate (butylacetate=1)
Not applicable
Melting point
318 °C
Freezing point
Not applicable
Boiling point
1380 °C
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
Not applicable
Flammability (solid, gas)
Not flammable
Vapour pressure
Not applicable
Relative vapour density at 20°C
Not applicable
Density
2.13 g/cm³
Solubility
111 g/100 mL in water at 20 °C
Log Pow
Not applicable
Viscosity, kinematic
Not applicable
Viscosity, dynamic
Not applicable
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Reacts violently with acids and generates heat upon contact with water.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Acids, organic materials, and metals.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Oral LD50 (rat): 325 mg/kg.
Skin corrosion/irritation
Causes severe skin burns and eye damage.
Serious eye damage/irritation
Causes serious eye damage.
Respiratory or skin sensitisation
Not a skin sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
May cause respiratory irritation.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
1823
UN-No. (IMDG)
1823
UN-No. (IATA)
1823
UN-No. (ADN)
1823
UN-No. (RID)
1823

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Sodium Hydroxide
Proper Shipping Name (IMDG)
Sodium Hydroxide
Proper Shipping Name (IATA)
Sodium Hydroxide
Proper Shipping Name (ADN)
Sodium Hydroxide
Proper Shipping Name (RID)
Sodium Hydroxide

14.3 — Transport hazard class(es)

Transport hazard class(es)
8

14.4 — Packing group

Packing group (ADR)
II
Packing group (IMDG)
II
Packing group (IATA)
II
Packing group (ADN)
II
Packing group (RID)
II

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Sodium hydroxide is extensively used in molecular biology for various applications, including alkaline lysis plasmid extraction, where it helps to lyse bacterial cells and release plasmid DNA. It is also utilized in RNA denaturation protocols, where it aids in the denaturation of RNA molecules for subsequent analysis. Beyond molecular biology, sodium hydroxide is employed in the manufacture of soaps, detergents, and paper, as well as in water treatment processes and chemical synthesis.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL1383A
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
40.00 g/mol
Test Standard Observed
Assay Purity 98% min 98.5%
Moisture Content <0.5% 0.3%
Residue on Ignition <0.1% 0.05%
Related Substances None detected None detected
Solubility Soluble in water Fully soluble

The above product is expected to comply with For Molecular Biology grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
For Molecular Biology 98% 318 °C / 1380 °C <0.5% <0.1% None detected Soluble in water
View full Technical Data Sheet

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