Tetracycline
- CAS Number
- 60-54-8
- HSN Code
- 29413090
- Molecular Formula
- C22H24N2O8·xH2O
- Catalogue Number
- AL1498B
- Purity
- ≥ 98%
- Molecular Weight
- 444.43 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Tetracycline base (for lab use) is a broad-spectrum antibiotic that gave its name to an entire class of antibiotics. It is derived from the bacterium Streptomyces aureofaciens and is known for its ability to inhibit protein synthesis in bacteria, making it effective against a wide range of gram-positive and gram-negative bacteria. Tetracycline is particularly notable for its use in treating infections, acne, and certain types of bacterial diseases. This product is provided in a 98% purity grade, suitable for laboratory applications and research purposes.
Also known as Tetracycline hydrochloride, Tetracycline base.
- Catalogue No.
- AL1498B
- CAS Number
- 60-54-8
- Molecular Formula
- C22H24N2O8·xH2O
- Molecular Weight
- 444.43 g/mol
- HSN Code
- 29413090
- Grade
- 98%
- Product Form
- Substance
Tetracycline appears as a yellow crystalline powder that is light-sensitive, requiring careful handling to avoid degradation. It has a melting point of approximately 155-160 °C and is slightly soluble in water, with a solubility of about 1 g in 100 mL of water at room temperature. The compound has a density of approximately 1.5 g/cm³. It is also known to be soluble in organic solvents such as ethanol and methanol, which can be useful for various laboratory applications.
- Appearance
- Yellow crystalline powder
- Shelf Life
- 2 years
- Packaging
- Available in 25 g and 100 g glass bottles
- Storage
- Store in a cool, dry place, protected from light.
1.1 — Product identifier
- Chemical Name
- Tetracycline
- Catalogue No.
- AL1498B
- Product form
- Substance
- CAS Number
- 60-54-8
- EC Number
- 200-578-6
- Grade
- 98%
- EC Index Number
- 607-115-00-0
- Chemical Formula
- C22H24N2O8·xH2O
- HSN Code
- 29413090
- Synonyms
- Tetracycline hydrochloride, Tetracycline base
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Antibiotic for laboratory use
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- May cause photosensitivity; handle with care.
3.1 — Substance
- Name
- Tetracycline
- CAS No.
- 60-54-8
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention if irritation persists.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Nausea, vomiting, diarrhea, and photosensitivity reactions.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes in a fire. Use water spray, foam, or dry chemical to extinguish.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and collect using appropriate protective equipment. Dispose of in accordance with local regulations.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Clean up spills immediately, using appropriate protective equipment. Avoid release into the environment.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Handle with gloves and avoid exposure to light. Use in a well-ventilated area.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from light and moisture.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if dust is generated.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- Yellow
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 155-160 °C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.5 g/cm³
- Solubility
- Slightly soluble in water, soluble in ethanol and methanol
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidising
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under recommended storage conditions.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids, and bases.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 (oral, rat) = 2,000 mg/kg.
- Skin corrosion/irritation
- May cause skin irritation.
- Serious eye damage/irritation
- May cause eye irritation.
- Respiratory or skin sensitisation
- Not a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not assigned
- UN-No. (IMDG)
- Not assigned
- UN-No. (IATA)
- Not assigned
- UN-No. (ADN)
- Not assigned
- UN-No. (RID)
- Not assigned
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not classified as dangerous goods
- Proper Shipping Name (IMDG)
- Not classified as dangerous goods
- Proper Shipping Name (IATA)
- Not classified as dangerous goods
- Proper Shipping Name (ADN)
- Not classified as dangerous goods
- Proper Shipping Name (RID)
- Not classified as dangerous goods
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Tetracycline is widely used as a reference standard in pharmaceutical quality control, particularly in the analysis of antibiotic formulations. It is also employed in tetracycline antibiotic research, where it serves as a model compound for studying antibiotic resistance and the mechanisms of action of antibiotics. Additionally, tetracycline is utilized in microbiological studies to assess bacterial susceptibility and in the development of new antibiotic formulations. Its applications extend to veterinary medicine, where it is used to treat infections in livestock and pets.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1498B
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 444.43 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 98% | 98.5% |
| Moisture Content | ≤ 1% | 0.5% |
| Residue on Ignition | ≤ 0.5% | 0.3% |
| Related Substances | None detected | None detected |
| Solubility | Slightly soluble in water | Slightly soluble |
The above product is expected to comply with 98% grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% | ≥ 98% | 155-160 °C | ≤ 1% | ≤ 0.5% | None detected | Slightly soluble in water, soluble in ethanol and methanol |
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