1-Hydroxy benzotriazole hydrate
- CAS Number
- 123333-53-9
- HSN Code
- 29339900
- Molecular Formula
- C6H5N3O·xH2O
- Catalogue Number
- AL0814B
- Purity
- ≥ 98%
- Molecular Weight
- 135.12 g/mol (anhydrous basis)
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
1-Hydroxy benzotriazole (HOBt) hydrate is a safer-to-handle form of HOBt that retains its utility in peptide coupling reactions. It is commonly used in organic synthesis, particularly in the formation of peptide bonds.
Also known as HOBt hydrate.
- Catalogue No.
- AL0814B
- CAS Number
- 123333-53-9
- Molecular Formula
- C6H5N3O·xH2O
- Molecular Weight
- 135.12 g/mol (anhydrous basis)
- HSN Code
- 29339900
- Grade
- 98% For Synthesis
- Product Form
- Substance
This compound appears as a white to pale yellow crystalline solid that is moist. It is hygroscopic and should be stored in a dry environment to maintain its integrity.
- Appearance
- White to pale yellow crystalline solid
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place away from heat and ignition sources.
1.1 — Product identifier
- Chemical Name
- 1-Hydroxy benzotriazole hydrate
- Catalogue No.
- AL0814B
- Product form
- Substance
- CAS Number
- 123333-53-9
- EC Number
- Not specified
- Grade
- 98% For Synthesis
- EC Index Number
- Not specified
- Chemical Formula
- C6H5N3O·xH2O
- HSN Code
- 29339900
- Synonyms
- HOBt hydrate
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used in peptide coupling reactions in organic synthesis.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Flammable solid; may cause skin and eye irritation.
3.1 — Substance
- Name
- 1-Hydroxy benzotriazole hydrate
- CAS No.
- 123333-53-9
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Irritation of eyes, skin, and respiratory tract; headache; dizziness.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Flammable solid; may produce toxic fumes in a fire.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and eliminate all ignition sources. Use appropriate protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Sweep up and place in a suitable container for disposal. Avoid generating dust.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use in a well-ventilated area and avoid inhalation of dust.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place away from heat and ignition sources.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if dust is generated.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White to pale yellow
- Odour
- Odourless
- Odour threshold
- Not specified
- pH value
- Not specified
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- Not specified
- Freezing point
- Not specified
- Boiling point
- Not specified
- Flash point
- Not specified
- Auto-ignition temperature
- Not specified
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Flammable solid
- Vapour pressure
- Not specified
- Relative vapour density at 20°C
- Not specified
- Density
- Not specified
- Solubility
- Soluble in water and organic solvents
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not specified
- Oxidising properties
- Not specified
- Explosive limits
- Not specified
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid heat and ignition sources.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Not specified
- Skin corrosion/irritation
- May cause skin irritation.
- Serious eye damage/irritation
- May cause eye irritation.
- Respiratory or skin sensitisation
- Not specified
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not specified
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 3474
- UN-No. (IMDG)
- UN 3474
- UN-No. (IATA)
- UN 3474
- UN-No. (ADN)
- UN 3474
- UN-No. (RID)
- UN 3474
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- 1-Hydroxy benzotriazole hydrate
- Proper Shipping Name (IMDG)
- 1-Hydroxy benzotriazole hydrate
- Proper Shipping Name (IATA)
- 1-Hydroxy benzotriazole hydrate
- Proper Shipping Name (ADN)
- 1-Hydroxy benzotriazole hydrate
- Proper Shipping Name (RID)
- 1-Hydroxy benzotriazole hydrate
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 4.1
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
1-Hydroxy benzotriazole hydrate is primarily used in peptide coupling reactions in organic synthesis, providing a safer alternative to its anhydrous counterpart.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL0814B
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 135.12 g/mol (anhydrous basis)
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 98% | 98.5% |
| Appearance | White to pale yellow crystalline solid | White crystalline solid |
| Solubility | Soluble in water and organic solvents | Soluble in both water and ethanol |
| pH | Not applicable | Not applicable |
The above product is expected to comply with 98% For Synthesis grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% For Synthesis | ≥ 98% | Not specified | Not specified | Not specified | Not specified | Soluble in water and organic solvents |
Related Products
View AllWhy buy from Alpha Chemika
What Our Scientific & Industrial Customers Say
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
FAQs
Common Questions About Laboratory Chemicals & Solutions
Find answers to common questions about laboratory chemicals, product selection, documentation, ordering, and technical support. Whether you are sourcing chemicals for research, testing, education, manufacturing, or industrial applications, these FAQs can help you make informed purchasing decisions.
Alpha Chemika offers a wide range of laboratory chemicals, reagents, solvents, and specialty products for research, testing, educational, pharmaceutical, and industrial applications.
Product selection depends on factors such as application, required purity, grade, specifications, and intended use. Our team can help you identify suitable products based on your technical requirements.
Yes. Relevant product information and technical documentation can be provided to help you evaluate products for quality, handling, compliance, and application requirements.
Yes. You can share your product list, required quantities, specifications, and delivery requirements with our team for a tailored quotation.
Yes. We support requirements from research laboratories, educational institutions, pharmaceutical companies, manufacturers, distributors, and other scientific and industrial organizations.
Connect with Us for Your Requirements
Have a specific product requirement or need help finding the right chemical for your application? Share your requirements with our team, and we will help you identify suitable products, specifications, quantities, and procurement options.
