Bis(2-chloroethyl)amine hydrochloride
- CAS Number
- 821-48-7
- HSN Code
- 29420090
- Molecular Formula
- C4H9Cl2N·HCl
- Catalogue Number
- AL1923C
- Purity
- ≥ 98%
- Molecular Weight
- 178.49 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Bis(2-chloroethyl)amine hydrochloride is a nitrogen mustard-related compound used as a synthetic intermediate under controlled conditions. It is primarily utilized in pharmaceutical and chemotherapy-related research due to its alkylating properties.
Also known as N,N-bis(2-chloroethyl)amine hydrochloride.
- Catalogue No.
- AL1923C
- CAS Number
- 821-48-7
- Molecular Formula
- C4H9Cl2N·HCl
- Molecular Weight
- 178.49 g/mol
- HSN Code
- 29420090
- Grade
- 98%
- Product Form
- Substance
White to pale tan crystalline powder; soluble in water. It has a melting point of approximately 150-155 °C and a boiling point of 220 °C.
- Appearance
- White to pale tan crystalline powder
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place, away from incompatible materials.
1.1 — Product identifier
- Chemical Name
- Bis(2-chloroethyl)amine hydrochloride
- Catalogue No.
- AL1923C
- Product form
- Substance
- CAS Number
- 821-48-7
- EC Number
- 212-828-1
- Grade
- 98%
- EC Index Number
- Not specified
- Chemical Formula
- C4H9Cl2N·HCl
- HSN Code
- 29420090
- Synonyms
- N,N-bis(2-chloroethyl)amine hydrochloride
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Synthetic intermediate in pharmaceutical applications
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Corrosive and highly toxic; may cause severe burns.
3.1 — Substance
- Name
- Bis(2-chloroethyl)amine hydrochloride
- CAS No.
- 821-48-7
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention immediately.
- First-aid measures after skin contact
- Remove contaminated clothing and wash skin thoroughly with soap and water. Seek medical attention if irritation persists.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and seek medical attention.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Symptoms may include respiratory distress, skin burns, and eye damage.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes under fire conditions. Use water spray to cool containers.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Wear appropriate protective equipment. Contain spill and absorb with inert material.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Collect and dispose of in accordance with local regulations. Avoid release into the environment.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Handle under controlled conditions with appropriate PPE in a fume hood. Avoid contact with skin and eyes.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials such as strong oxidizers.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection when handling this substance.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White to pale tan
- Odour
- Not specified
- Odour threshold
- Not specified
- pH value
- Not specified
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- 150-155 °C
- Freezing point
- Not specified
- Boiling point
- 220 °C
- Flash point
- Not specified
- Auto-ignition temperature
- Not specified
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable under normal conditions.
- Vapour pressure
- Not specified
- Relative vapour density at 20°C
- Not specified
- Density
- Not specified
- Solubility
- Soluble in water
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not specified
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid contact with strong oxidizers.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Highly toxic; may cause severe health effects upon exposure.
- Skin corrosion/irritation
- Causes severe skin burns and eye damage.
- Serious eye damage/irritation
- Causes serious eye damage.
- Respiratory or skin sensitisation
- Not classified as a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 1759
- UN-No. (IMDG)
- UN 1759
- UN-No. (IATA)
- UN 1759
- UN-No. (ADN)
- UN 1759
- UN-No. (RID)
- UN 1759
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Corrosive solid, n.o.s. (Bis(2-chloroethyl)amine hydrochloride)
- Proper Shipping Name (IMDG)
- Corrosive solid, n.o.s. (Bis(2-chloroethyl)amine hydrochloride)
- Proper Shipping Name (IATA)
- Corrosive solid, n.o.s. (Bis(2-chloroethyl)amine hydrochloride)
- Proper Shipping Name (ADN)
- Corrosive solid, n.o.s. (Bis(2-chloroethyl)amine hydrochloride)
- Proper Shipping Name (RID)
- Corrosive solid, n.o.s. (Bis(2-chloroethyl)amine hydrochloride)
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 8
14.4 — Packing group
- Packing group (ADR)
- II
- Packing group (IMDG)
- II
- Packing group (IATA)
- II
- Packing group (ADN)
- II
- Packing group (RID)
- II
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as a controlled synthetic intermediate in specialized pharmaceutical and chemotherapy-related research.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1923C
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 178.49 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 98% | 98.5% |
| Melting Point | 150-155 °C | 152 °C |
| Moisture Content | ≤ 0.5% | 0.3% |
| Residue on Ignition | ≤ 0.1% | 0.05% |
| Related Substances | Not more than 0.5% | 0.2% |
The above product is expected to comply with 98% grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% | ≥ 98% | 150-155 °C | ≤ 0.5% | ≤ 0.1% | Not more than 0.5% | Soluble in water |
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