Ethyl Chloroformate
- CAS Number
- 541-41-3
- HSN Code
- 29153990
- Molecular Formula
- C3H5ClO2
- Catalogue Number
- AL00686
- Purity
- ≥ 97%
- Molecular Weight
- 108.32 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Ethyl chloroformate is a reactive mixed carbonate/chloride reagent widely used in mixed-anhydride peptide coupling and ester synthesis.
Also known as Ethyl chloroformate, Ethyl chloroformate reagent.
- Catalogue No.
- AL00686
- CAS Number
- 541-41-3
- Molecular Formula
- C3H5ClO2
- Molecular Weight
- 108.32 g/mol
- HSN Code
- 29153990
- Grade
- 97% For Synthesis
- Product Form
- Substance
Colorless to pale yellow liquid with a density of 1.135 g/mL and a pungent odor.
- Appearance
- Colorless to pale yellow liquid
- Shelf Life
- 12 months
- Packaging
- Available in 500 mL glass bottles
- Storage
- Store in a cool, dry place away from heat and incompatible materials.
1.1 — Product identifier
- Chemical Name
- Ethyl Chloroformate
- Catalogue No.
- AL00686
- Product form
- Substance
- CAS Number
- 541-41-3
- EC Number
- 208-703-4
- Grade
- 97% For Synthesis
- EC Index Number
- 607-007-00-8
- Chemical Formula
- C3H5ClO2
- HSN Code
- 29153990
- Synonyms
- Ethyl chloroformate, Ethyl chloroformate reagent
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Reagent for organic synthesis, particularly in peptide coupling and ester synthesis.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- May cause respiratory irritation; may be harmful if inhaled.
3.1 — Substance
- Name
- Ethyl Chloroformate
- CAS No.
- 541-41-3
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. Remove contaminated clothing. Seek medical attention if irritation persists.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Coughing, shortness of breath, skin irritation, eye irritation.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Highly flammable. Vapors may form explosive mixtures with air.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area. Ventilate. Use appropriate protective equipment. Contain spill.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Absorb with inert material and dispose of in accordance with local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood with appropriate PPE including gloves and goggles.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from heat sources and incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use NIOSH-approved respirator if exposure limits are exceeded.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless to pale yellow
- Odour
- Pungent
- Odour threshold
- No data available
- pH value
- No data available
- Relative evaporation rate (butylacetate=1)
- No data available
- Melting point
- -80 °C
- Freezing point
- No data available
- Boiling point
- 97 °C
- Flash point
- 10 °C
- Auto-ignition temperature
- No data available
- Decomposition temperature
- No data available
- Flammability (solid, gas)
- Flammable liquid
- Vapour pressure
- No data available
- Relative vapour density at 20°C
- No data available
- Density
- 1.135 g/mL
- Solubility
- Soluble in organic solvents, insoluble in water
- Log Pow
- No data available
- Viscosity, kinematic
- No data available
- Viscosity, dynamic
- No data available
- Explosive properties
- No data available
- Oxidising properties
- No data available
- Explosive limits
- No data available
10.1 — Reactivity
- Reactivity
- Reacts violently with strong bases and oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, strong bases, amines, alcohols.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Highly toxic; LD50 (oral, rat) 50 mg/kg.
- Skin corrosion/irritation
- Causes skin irritation.
- Serious eye damage/irritation
- Causes serious eye damage.
- Respiratory or skin sensitisation
- May cause allergic skin reaction.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 1182
- UN-No. (IMDG)
- UN 1182
- UN-No. (IATA)
- UN 1182
- UN-No. (ADN)
- UN 1182
- UN-No. (RID)
- UN 1182
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Ethyl Chloroformate
- Proper Shipping Name (IMDG)
- Ethyl Chloroformate
- Proper Shipping Name (IATA)
- Ethyl Chloroformate
- Proper Shipping Name (ADN)
- Ethyl Chloroformate
- Proper Shipping Name (RID)
- Ethyl Chloroformate
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Used as an activating reagent in mixed-anhydride peptide coupling reactions and carbamate/carbonate ester synthesis.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL00686
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 108.32 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | A clear colorless liquid | A clear colorless liquid |
| Assay (GC) | Min 98% | 98.39% |
| D20°/4° | 1.138-1.140g | 1.139g |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 97% For Synthesis | ≥ 97% | Boiling point: 97 °C | ≤ 0.5% | ≤ 0.1% | None detected | Soluble in organic solvents |
Related Products
View AllWhy buy from Alpha Chemika
What Our Scientific & Industrial Customers Say
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“One shop stop for all laboratory chemicals requirements.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“Exactly as advertised.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Alpha Chemika products are of excellent quality. Highly satisfied.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“From ordering to shipping, every course of action was smooth. Timely delivery.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“Completely satisfied with the products and services.”
“Speedy delivery, professional staff.”
“One shop stop for all laboratory chemicals requirements.”
FAQs
Common Questions About Laboratory Chemicals & Solutions
Find answers to common questions about laboratory chemicals, product selection, documentation, ordering, and technical support. Whether you are sourcing chemicals for research, testing, education, manufacturing, or industrial applications, these FAQs can help you make informed purchasing decisions.
Alpha Chemika offers a wide range of laboratory chemicals, reagents, solvents, and specialty products for research, testing, educational, pharmaceutical, and industrial applications.
Product selection depends on factors such as application, required purity, grade, specifications, and intended use. Our team can help you identify suitable products based on your technical requirements.
Yes. Relevant product information and technical documentation can be provided to help you evaluate products for quality, handling, compliance, and application requirements.
Yes. You can share your product list, required quantities, specifications, and delivery requirements with our team for a tailored quotation.
Yes. We support requirements from research laboratories, educational institutions, pharmaceutical companies, manufacturers, distributors, and other scientific and industrial organizations.
Connect with Us for Your Requirements
Have a specific product requirement or need help finding the right chemical for your application? Share your requirements with our team, and we will help you identify suitable products, specifications, quantities, and procurement options.
