Hydrocortisone

99% For Laboratory Use
CAS Number
50-23-7
HSN Code
29372100
Molecular Formula
C21H30O5
Catalogue Number
AL0808B
Purity
≥ 99%
Molecular Weight
362.46 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White crystalline powder
Shelf Life 2 years
Packaging 25 g in glass bottle
Storage Store in a cool, dry place, away from light.

Hydrocortisone (cortisol) is the primary glucocorticoid hormone produced by the adrenal glands, essential to stress response and metabolism regulation.

Also known as Cortisol.

Catalogue No.
AL0808B
CAS Number
50-23-7
Molecular Formula
C21H30O5
Molecular Weight
362.46 g/mol
HSN Code
29372100
Grade
99%
Product Form
Substance

White crystalline powder; practically insoluble in water.

Appearance
White crystalline powder
Shelf Life
2 years
Packaging
25 g in glass bottle
Storage
Store in a cool, dry place, away from light.

1.1 — Product identifier

Chemical Name
Hydrocortisone
Catalogue No.
AL0808B
Product form
Substance
CAS Number
50-23-7
EC Number
200-001-8
Grade
99%
EC Index Number
Not applicable
Chemical Formula
C21H30O5
HSN Code
29372100
Synonyms
Cortisol

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Pharmaceutical reference standard
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
None known

3.1 — Substance

Name
Hydrocortisone
CAS No.
50-23-7

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. Seek medical attention if symptoms persist.
First-aid measures after skin contact
Wash with soap and water. Seek medical attention if irritation develops.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention if irritation persists.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. Seek medical attention.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
May cause skin irritation or allergic reactions in sensitive individuals.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Combustible material; may produce toxic fumes when burned.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and collect using appropriate protective equipment. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Use inert absorbent material and place in a suitable container for disposal.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Handle with gloves and avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place, away from light and moisture.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Not required under normal conditions of use.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White
Odour
Odourless
Odour threshold
Not applicable
pH value
Not applicable
Relative evaporation rate (butylacetate=1)
Not applicable
Melting point
215-220 °C
Freezing point
Not applicable
Boiling point
Not applicable
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
Not applicable
Flammability (solid, gas)
Not flammable
Vapour pressure
Not applicable
Relative vapour density at 20°C
Not applicable
Density
1.25 g/cm³
Solubility
Practically insoluble in water; soluble in ethanol and acetone
Log Pow
Not applicable
Viscosity, kinematic
Not applicable
Viscosity, dynamic
Not applicable
Explosive properties
Not explosive
Oxidising properties
Not oxidising
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Stable under normal conditions.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizing agents.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
LD50 (oral, rat) 300 mg/kg
Skin corrosion/irritation
May cause mild irritation.
Serious eye damage/irritation
May cause mild irritation.
Respiratory or skin sensitisation
Not a sensitizer in normal use.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
Not classified as a specific target organ toxicant.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
Not assigned
UN-No. (IMDG)
Not assigned
UN-No. (IATA)
Not assigned
UN-No. (ADN)
Not assigned
UN-No. (RID)
Not assigned

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Not classified as dangerous goods
Proper Shipping Name (IMDG)
Not classified as dangerous goods
Proper Shipping Name (IATA)
Not classified as dangerous goods
Proper Shipping Name (ADN)
Not classified as dangerous goods
Proper Shipping Name (RID)
Not classified as dangerous goods

14.3 — Transport hazard class(es)

Transport hazard class(es)
Not applicable

14.4 — Packing group

Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Used as a reference standard in pharmaceutical corticosteroid quality control and endocrinology research.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL0808B
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
362.46 g/mol
Test Standard Observed
Assay ≥ 99% 99.5%
Moisture Content ≤ 0.5% 0.3%
Residue on Ignition ≤ 0.1% 0.05%
Related Substances None detected None detected

The above product is expected to comply with 99% grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
99% ≥ 99% 215-220 °C ≤ 0.5% ≤ 0.1% None detected Practically insoluble in water; soluble in ethanol and acetone
View full Technical Data Sheet

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