p-Toluidine hydrochloride

For Synthesis For Laboratory Use
CAS Number
540-23-8
HSN Code
29214350
Molecular Formula
C7H9N·HCl
Catalogue Number
AL02578
Purity
≥ 99%
Molecular Weight
143.62 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White to pale gray crystalline powder
Shelf Life 2 years
Packaging Available in 100g, 500g, and 1kg containers
Storage Store in a cool, dry place, away from moisture and incompatible materials.

p-Toluidine hydrochloride (for synthesis) is a stable salt form of p-toluidine, a colorless to pale yellow liquid amine. It is primarily used as a synthetic intermediate in the production of various chemical compounds. This compound is notable for its role in the synthesis of azo dyes and pharmaceuticals, making it an important reagent in organic chemistry. With a high purity of 99%, it is suitable for laboratory and industrial applications where precision and quality are paramount.

Also known as p-Toluidine HCl, 4-Methylaminobenzene hydrochloride.

Catalogue No.
AL02578
CAS Number
540-23-8
Molecular Formula
C7H9N·HCl
Molecular Weight
143.62 g/mol
HSN Code
29214350
Grade
For Synthesis
Product Form
Substance

p-Toluidine hydrochloride appears as a white to pale gray crystalline powder. It has a melting point of approximately 170-175 °C and is soluble in water, which facilitates its use in various aqueous reactions. The compound has a density of about 1.1 g/cm³ and exhibits a slight amine-like odor. Its hygroscopic nature means it can absorb moisture from the air, which should be considered during storage and handling.

Appearance
White to pale gray crystalline powder
Shelf Life
2 years
Packaging
Available in 100g, 500g, and 1kg containers
Storage
Store in a cool, dry place, away from moisture and incompatible materials.

1.1 — Product identifier

Chemical Name
p-Toluidine hydrochloride
Catalogue No.
AL02578
Product form
Substance
CAS Number
540-23-8
EC Number
208-963-0
Grade
For Synthesis
EC Index Number
612-007-00-6
Chemical Formula
C7H9N·HCl
HSN Code
29214350
Synonyms
p-Toluidine HCl, 4-Methylaminobenzene hydrochloride

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used as a synthetic intermediate in the production of dyes and pharmaceuticals.
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
Suspected carcinogen; may cause skin and eye irritation.

3.1 — Substance

Name
p-Toluidine hydrochloride
CAS No.
540-23-8

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion
Do not induce vomiting. Rinse mouth and seek medical attention immediately.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
Symptoms of exposure may include headache, dizziness, nausea, and skin irritation.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Toxic fumes may be released in a fire. Use appropriate fire-fighting measures.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Evacuate area and ventilate. Wear appropriate protective equipment.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Contain spill and collect using appropriate methods. Dispose of in accordance with local regulations.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Handle with gloves and in a well-ventilated area. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place, away from incompatible materials such as strong oxidizers.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use appropriate respiratory protection if ventilation is inadequate.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White to pale gray
Odour
Slight amine-like
Odour threshold
Not specified
pH value
Not specified
Relative evaporation rate (butylacetate=1)
Not specified
Melting point
170-175 °C
Freezing point
Not specified
Boiling point
Not specified
Flash point
Not specified
Auto-ignition temperature
Not specified
Decomposition temperature
Not specified
Flammability (solid, gas)
Not flammable under normal conditions
Vapour pressure
Not specified
Relative vapour density at 20°C
Not specified
Density
1.1 g/cm³
Solubility
Soluble in water
Log Pow
Not specified
Viscosity, kinematic
Not specified
Viscosity, dynamic
Not specified
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not specified

10.1 — Reactivity

Reactivity
Stable under normal conditions; avoid strong oxidizing agents.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizing agents, strong acids.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Toxic if swallowed or inhaled; may cause respiratory irritation.
Skin corrosion/irritation
Causes skin irritation.
Serious eye damage/irritation
Causes serious eye irritation.
Respiratory or skin sensitisation
May cause allergic skin reaction.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
May cause damage to organs through prolonged or repeated exposure.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
2811
UN-No. (IMDG)
2811
UN-No. (IATA)
2811
UN-No. (ADN)
2811
UN-No. (RID)
2811

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Toxic solid, organic, n.o.s. (p-Toluidine hydrochloride)
Proper Shipping Name (IMDG)
Toxic solid, organic, n.o.s. (p-Toluidine hydrochloride)
Proper Shipping Name (IATA)
Toxic solid, organic, n.o.s. (p-Toluidine hydrochloride)
Proper Shipping Name (ADN)
Toxic solid, organic, n.o.s. (p-Toluidine hydrochloride)
Proper Shipping Name (RID)
Toxic solid, organic, n.o.s. (p-Toluidine hydrochloride)

14.3 — Transport hazard class(es)

Transport hazard class(es)
6.1

14.4 — Packing group

Packing group (ADR)
III
Packing group (IMDG)
III
Packing group (IATA)
III
Packing group (ADN)
III
Packing group (RID)
III

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

p-Toluidine hydrochloride is widely used as a building block in the synthesis of azo dyes, which are important in the textile industry for coloring fabrics. Additionally, it serves as a pharmaceutical intermediate in the production of various drugs, including analgesics and anti-inflammatory agents. Its applications extend to research settings where it is utilized in organic synthesis and chemical analysis, making it a versatile compound in both industrial and laboratory environments.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL02578
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
143.62 g/mol
Test Standard Observed
Description Light brownish flakes/powder Light brownish flakes
Assay (by argentometry) Min. 99.0% 99.1%
Melting range 239 - 242°C Light brownish flakes 240°C
Light brownish flakes

The above product complies with LR grade

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
For Synthesis ≥ 99% 170-175 °C ≤ 0.5% ≤ 0.1% None detected Soluble in water
View full Technical Data Sheet

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