Polyvinylpyrrolidone (PVP)

For Molecular Biology For Laboratory Use
CAS Number
9003-39-8
HSN Code
39059910
Molecular Formula
(C6H9NO)n
Catalogue Number
AL1216A
Purity
≥ 98%
Molecular Weight
40000 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White to off-white powder
Shelf Life -
Packaging -
Storage Store in a cool, dry place away from direct sunlight.

Polyvinylpyrrolidone (PVP, M.W. 40,000, for molecular biology) is a widely used water-soluble polymer valued for its ability to bind polyphenolic compounds. It is a synthetic polymer that is non-toxic and biocompatible, making it suitable for various applications in the biomedical field. PVP is known for its excellent solubility in water and a variety of organic solvents, which enhances its versatility in laboratory settings. Its unique properties allow it to stabilize proteins and other biomolecules, making it an essential reagent in molecular biology and biochemistry.

Also known as PVP, Povidone.

Catalogue No.
AL1216A
CAS Number
9003-39-8
Molecular Formula
(C6H9NO)n
Molecular Weight
40000 g/mol
HSN Code
39059910
Grade
For Molecular Biology
Product Form
Substance

Polyvinylpyrrolidone appears as a white to off-white powder. It is highly soluble in water, with solubility exceeding 100 g/L at room temperature. The polymer has a melting point of approximately 200 °C, and it decomposes upon heating rather than melting. PVP has a density of about 1.2 g/cm³. It is odorless and has a neutral pH when dissolved in water. The polymer exhibits low viscosity in solution, which is advantageous for various applications in molecular biology.

Appearance
White to off-white powder
Shelf Life
-
Packaging
-
Storage
Store in a cool, dry place away from direct sunlight.

1.1 — Product identifier

Chemical Name
Polyvinylpyrrolidone (PVP)
Catalogue No.
AL1216A
Product form
Substance
CAS Number
9003-39-8
EC Number
None assigned
Grade
For Molecular Biology
EC Index Number
None assigned
Chemical Formula
(C6H9NO)n
HSN Code
39059910
Synonyms
PVP, Povidone

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used in molecular biology for DNA/RNA extraction and as a stabilizer in various formulations.
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
None known under normal handling conditions.

3.1 — Substance

Name
Polyvinylpyrrolidone (PVP)
CAS No.
9003-39-8

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
No specific symptoms expected under normal use; may cause mild irritation in sensitive individuals.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Combustible material; may produce toxic fumes when burned.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and collect using appropriate methods. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place, away from incompatible materials.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Not required under normal use; use in well-ventilated areas.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White to off-white
Odour
Odourless
Odour threshold
Not applicable
pH value
Neutral
Relative evaporation rate (butylacetate=1)
Not applicable
Melting point
200 °C (decomposes)
Freezing point
Not applicable
Boiling point
Not applicable
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
>200 °C
Flammability (solid, gas)
Combustible
Vapour pressure
Not applicable
Relative vapour density at 20°C
Not applicable
Density
1.2 g/cm³
Solubility
>100 g/L in water
Log Pow
Not applicable
Viscosity, kinematic
Not applicable
Viscosity, dynamic
Not applicable
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Stable under normal conditions.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizing agents.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Not classified as acutely toxic.
Skin corrosion/irritation
May cause mild irritation in sensitive individuals.
Serious eye damage/irritation
May cause mild irritation.
Respiratory or skin sensitisation
Not expected to be a sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
Not classified as a specific target organ toxicant.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
Not assigned
UN-No. (IMDG)
Not assigned
UN-No. (IATA)
Not assigned
UN-No. (ADN)
Not assigned
UN-No. (RID)
Not assigned

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Not classified as dangerous goods
Proper Shipping Name (IMDG)
Not classified as dangerous goods
Proper Shipping Name (IATA)
Not classified as dangerous goods
Proper Shipping Name (ADN)
Not classified as dangerous goods
Proper Shipping Name (RID)
Not classified as dangerous goods

14.3 — Transport hazard class(es)

Transport hazard class(es)
Not applicable

14.4 — Packing group

Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Polyvinylpyrrolidone is primarily used in molecular biology for the removal of polyphenolic contaminants during DNA and RNA extraction protocols. Its ability to bind to polyphenols makes it invaluable in purifying nucleic acids from plant tissues, where such contaminants are prevalent. Additionally, PVP is utilized in the formulation of pharmaceuticals, cosmetics, and food products due to its stabilizing and thickening properties. In the laboratory, it serves as a protective colloid in various biochemical assays and as a component in drug delivery systems.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL1216A
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
40000 g/mol
Test Standard Observed
Assay Purity ≥ 98% 99.5%
Moisture Content < 5% 3.2%
Residue on Ignition < 0.1% 0.05%
Solubility >100 g/L in water >100 g/L in water

The above product is expected to comply with For Molecular Biology grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
For Molecular Biology ≥ 98% 200 °C (decomposes) < 5% < 0.1% None detected >100 g/L in water
View full Technical Data Sheet

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