Progesterone
- CAS Number
- 57-83-0
- HSN Code
- 29372300
- Molecular Formula
- C21H30O2
- Catalogue Number
- AL2485D
- Purity
- 97% min
- Molecular Weight
- 314.46 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Progesterone (for biochemistry) is a key steroid hormone essential to the menstrual cycle, pregnancy, and embryogenesis. It plays a crucial role in regulating various physiological processes, including the menstrual cycle and maintaining pregnancy. This compound is classified as a steroid and is vital for reproductive health. With a purity of 97%, this grade of progesterone is suitable for biochemical applications, particularly in research and quality control settings.
Also known as Pregn-4-ene-3,20-dione; 17-Hydroxyprogesterone; 4-Pregnen-3,20-dione.
- Catalogue No.
- AL2485D
- CAS Number
- 57-83-0
- Molecular Formula
- C21H30O2
- Molecular Weight
- 314.46 g/mol
- HSN Code
- 29372300
- Grade
- 97%
- Product Form
- Substance
Progesterone appears as a white crystalline powder, which is odorless and has a slightly sweet taste. It is insoluble in water but soluble in organic solvents such as ethanol and chloroform. The melting point of progesterone is approximately 124-127 °C, and it has a boiling point of about 330 °C at 760 mmHg. The density of progesterone is around 1.04 g/cm³. It has a refractive index of 1.487 and a flash point of 150 °C, indicating its stability under normal conditions.
- Appearance
- White crystalline powder
- Shelf Life
- 2 years
- Packaging
- 25 g in amber glass bottles
- Storage
- Store in a cool, dry place, away from light.
1.1 — Product identifier
- Chemical Name
- Progesterone
- Catalogue No.
- AL2485D
- Product form
- Substance
- CAS Number
- 57-83-0
- EC Number
- 200-350-8
- Grade
- 97%
- EC Index Number
- 607-003-00-4
- Chemical Formula
- C21H30O2
- HSN Code
- 29372300
- Synonyms
- Pregn-4-ene-3,20-dione; 17-Hydroxyprogesterone; 4-Pregnen-3,20-dione
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used in biochemistry and pharmaceutical applications as a hormone standard.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- None identified; handle with care as it is a pharmacologically active compound.
3.1 — Substance
- Name
- Progesterone
- CAS No.
- 57-83-0
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- May cause skin irritation or allergic reactions in sensitive individuals.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Combustible material; may produce toxic fumes when burned.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and collect using appropriate protective equipment. Dispose of in accordance with local regulations.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use gloves and protective eyewear when handling.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from light and moisture.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Not required under normal conditions; use in well-ventilated areas.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 124-127 °C
- Freezing point
- Not applicable
- Boiling point
- 330 °C
- Flash point
- 150 °C
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Combustible solid
- Vapour pressure
- <0.01 mmHg at 25 °C
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.04 g/cm³
- Solubility
- Insoluble in water; soluble in ethanol and chloroform
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 (oral, rat) > 2000 mg/kg; low toxicity.
- Skin corrosion/irritation
- May cause mild irritation in sensitive individuals.
- Serious eye damage/irritation
- May cause mild irritation.
- Respiratory or skin sensitisation
- Not a sensitizer in normal use.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not classified as dangerous goods.
- UN-No. (IMDG)
- Not classified as dangerous goods.
- UN-No. (IATA)
- Not classified as dangerous goods.
- UN-No. (ADN)
- Not classified as dangerous goods.
- UN-No. (RID)
- Not classified as dangerous goods.
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Progesterone
- Proper Shipping Name (IMDG)
- Progesterone
- Proper Shipping Name (IATA)
- Progesterone
- Proper Shipping Name (ADN)
- Progesterone
- Proper Shipping Name (RID)
- Progesterone
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Progesterone is widely used as a reference standard in pharmaceutical hormone quality control, ensuring the accuracy and reliability of hormone assays. It is also utilized in endocrinology and reproductive biology research to study hormonal effects on the menstrual cycle, pregnancy, and embryonic development. Additionally, progesterone is employed in the formulation of hormone replacement therapies and contraceptives, making it significant in both clinical and research settings.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL2485D
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 314.46 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 97% min | 97.5% |
| Melting Point | 124-127 °C | 125 °C |
| Moisture Content | <0.5% | 0.3% |
| Residue on Ignition | <0.1% | 0.05% |
| Related Substances | <1% | 0.8% |
The above product is expected to comply with 97% grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 97% | 97% min | 124-127 °C | <0.5% | <0.1% | <1% | Insoluble in water, soluble in ethanol and chloroform |
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