Propyl-p-hydroxy benzoate sodium salt
- CAS Number
- 35285-69-9
- HSN Code
- 29182990
- Molecular Formula
- C10H11NaO3
- Catalogue Number
- AL1276B
- Purity
- 99%
- Molecular Weight
- 202.18 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Propyl-p-hydroxy benzoate sodium salt, also known as nipasol sodium, is a water-soluble sodium salt derivative of propylparaben. This compound is notable for its enhanced solubility in aqueous solutions, making it particularly useful in various formulations. With a high purity level of 99%, it is classified as extra pure, ensuring minimal impurities that could affect its performance in applications. The compound is widely utilized in the cosmetic and pharmaceutical industries as a preservative, helping to extend the shelf life of products by preventing microbial growth.
Also known as Nipasol sodium.
- Catalogue No.
- AL1276B
- CAS Number
- 35285-69-9
- Molecular Formula
- C10H11NaO3
- Molecular Weight
- 202.18 g/mol
- HSN Code
- 29182990
- Grade
- Extra Pure
- Product Form
- Substance
Propyl-p-hydroxy benzoate sodium salt appears as a white crystalline powder. It is freely soluble in water, which enhances its utility in formulations that require a water-soluble preservative. The melting point of this compound is approximately 200 °C, and it has a density of about 1.2 g/cm³. The compound has a neutral pH when dissolved in water, making it compatible with a wide range of formulations. Its solubility in water is a key characteristic that distinguishes it from its non-sodium counterparts, allowing for easier incorporation into aqueous systems.
- Appearance
- White crystalline powder
- Shelf Life
- 2 years
- Packaging
- Available in 100g, 500g, and 1kg containers
- Storage
- Store in a cool, dry place away from direct sunlight.
1.1 — Product identifier
- Chemical Name
- Propyl-p-hydroxy benzoate sodium salt
- Catalogue No.
- AL1276B
- Product form
- Substance
- CAS Number
- 35285-69-9
- EC Number
- 252-104-2
- Grade
- Extra Pure
- EC Index Number
- Not applicable
- Chemical Formula
- C10H11NaO3
- HSN Code
- 29182990
- Synonyms
- Nipasol sodium
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Preservative in cosmetic and pharmaceutical formulations
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- None identified
3.1 — Substance
- Name
- Propyl-p-hydroxy benzoate sodium salt
- CAS No.
- 35285-69-9
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- May cause mild irritation to skin and eyes.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Non-flammable under normal conditions.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and collect using appropriate methods. Dispose of in accordance with local regulations.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use in a well-ventilated area.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Not required under normal conditions of use.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Neutral
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 200 °C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.2 g/cm³
- Solubility
- Freely soluble in water
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Low toxicity; LD50 (oral, rat) > 5000 mg/kg.
- Skin corrosion/irritation
- May cause mild irritation.
- Serious eye damage/irritation
- May cause mild irritation.
- Respiratory or skin sensitisation
- Not a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not classified as dangerous goods.
- UN-No. (IMDG)
- Not classified as dangerous goods.
- UN-No. (IATA)
- Not classified as dangerous goods.
- UN-No. (ADN)
- Not classified as dangerous goods.
- UN-No. (RID)
- Not classified as dangerous goods.
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not applicable
- Proper Shipping Name (IMDG)
- Not applicable
- Proper Shipping Name (IATA)
- Not applicable
- Proper Shipping Name (ADN)
- Not applicable
- Proper Shipping Name (RID)
- Not applicable
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
This compound is primarily used as a water-soluble preservative in cosmetic and pharmaceutical formulations. It is effective in preventing the growth of bacteria, yeast, and mold, thereby extending the shelf life of products such as creams, lotions, and ointments. Additionally, propyl-p-hydroxy benzoate sodium salt is utilized in formulation research as a reference compound, aiding in the development of new products. Its solubility profile makes it suitable for use in various aqueous formulations, including gels and emulsions, where traditional preservatives may not be effective.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1276B
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 202.18 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 99% min | 99.5% |
| Moisture Content | <1% | 0.5% |
| Residue on Ignition | <0.1% | 0.05% |
| Related Substances | None detected | None detected |
The above product is expected to comply with Extra Pure grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| Extra Pure | 99% | 200 °C | <1% | <0.1% | None detected | Freely soluble in water |
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