Quinoline
- CAS Number
- 91-22-5
- HSN Code
- 29333919
- Molecular Formula
- C9H7N
- Catalogue Number
- AL01287
- Purity
- ≥ 97%
- Molecular Weight
- 129.16 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Quinoline is a fundamental bicyclic nitrogen heterocycle that serves as a crucial building block in various chemical syntheses. It is widely utilized as a solvent and synthetic intermediate in pharmaceutical and agrochemical chemistry. With a purity of 97%, Quinoline is recognized for its role in the synthesis of important compounds, including pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable compound in organic chemistry and industrial applications.
Also known as Quinoline, 1-Azabicyclo[2.2.1]hept-2-ene.
- Catalogue No.
- AL01287
- CAS Number
- 91-22-5
- Molecular Formula
- C9H7N
- Molecular Weight
- 129.16 g/mol
- HSN Code
- 29333919
- Grade
- 97%
- Product Form
- Substance
Quinoline appears as a colorless to pale yellow liquid with a density of 1.094 g/mL. It has a penetrating odor and is known to darken upon exposure to light. The boiling point of Quinoline is approximately 237 °C, and it has a melting point of -3.5 °C. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water. The refractive index is about 1.586, and it has a flash point of 102 °C, indicating its flammability under certain conditions.
- Appearance
- Colorless to pale yellow liquid
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place away from light.
1.1 — Product identifier
- Chemical Name
- Quinoline
- Catalogue No.
- AL01287
- Product form
- Substance
- CAS Number
- 91-22-5
- EC Number
- 202-051-0
- Grade
- 97%
- EC Index Number
- Not specified
- Chemical Formula
- C9H7N
- HSN Code
- 29333919
- Synonyms
- Quinoline, 1-Azabicyclo[2.2.1]hept-2-ene
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Solvent and synthetic intermediate in pharmaceuticals and agrochemicals
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Suspected carcinogen; handle with care.
3.1 — Substance
- Name
- Quinoline
- CAS No.
- 91-22-5
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Headache, dizziness, nausea, and skin irritation upon exposure.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Combustible liquid; may produce toxic fumes when burned.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Wear appropriate protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Contain spill and absorb with inert material. Dispose of in accordance with local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Use in a fume hood and wear appropriate personal protective equipment (PPE).
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from light and incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Liquid
- Colour
- Colorless to pale yellow
- Odour
- Penetrating
- Odour threshold
- Not specified
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- -3.5 °C
- Freezing point
- Not specified
- Boiling point
- 237 °C
- Flash point
- 102 °C
- Auto-ignition temperature
- Not specified
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Flammable liquid
- Vapour pressure
- 0.5 mmHg at 20 °C
- Relative vapour density at 20°C
- Not specified
- Density
- 1.094 g/mL
- Solubility
- Slightly soluble in water, soluble in organic solvents
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not specified
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizers, strong acids.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Toxic if swallowed, inhaled, or absorbed through skin.
- Skin corrosion/irritation
- Causes skin irritation.
- Serious eye damage/irritation
- Causes serious eye irritation.
- Respiratory or skin sensitisation
- May cause allergic skin reaction.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- 2656
- UN-No. (IMDG)
- 2656
- UN-No. (IATA)
- 2656
- UN-No. (ADN)
- 2656
- UN-No. (RID)
- 2656
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Quinoline
- Proper Shipping Name (IMDG)
- Quinoline
- Proper Shipping Name (IATA)
- Quinoline
- Proper Shipping Name (ADN)
- Quinoline
- Proper Shipping Name (RID)
- Quinoline
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- III
- Packing group (IMDG)
- III
- Packing group (IATA)
- III
- Packing group (ADN)
- III
- Packing group (RID)
- III
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Quinoline is extensively used as a high-boiling solvent in metal-catalyzed reactions, particularly in organic synthesis. It serves as a key building block in the synthesis of quinoline-based drugs, including chloroquine and various quinolone derivatives, which are significant in the treatment of malaria and bacterial infections. Additionally, Quinoline is employed in the production of dyes, agrochemicals, and as a corrosion inhibitor in industrial applications. Its versatility makes it an essential compound in both research and commercial settings.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL01287
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 129.16 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 97% | 97.5% |
| Density | 1.094 g/mL | 1.092 g/mL |
| Boiling Point | 237 °C | 236 °C |
| Melting Point | -3.5 °C | -3.2 °C |
| Moisture Content | ≤ 0.5% | 0.3% |
| Residue on Ignition | ≤ 0.1% | 0.05% |
| Related Substances | None detected | None detected |
The above product is expected to comply with 97% grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 97% | ≥ 97% | -3.5 °C / 237 °C | ≤ 0.5% | ≤ 0.1% | None detected | Slightly soluble in water, soluble in organic solvents |
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