Reserpine
- CAS Number
- 50-55-5
- HSN Code
- 29362990
- Molecular Formula
- C33H40N2O9
- Catalogue Number
- AL1287D
- Purity
- ≥ 97.5%
- Molecular Weight
- 608.70 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Reserpine is a natural alkaloid derived from the plant Rauwolfia serpentina, historically utilized for its antihypertensive properties. It functions primarily by depleting neurotransmitter stores, particularly norepinephrine, leading to a reduction in blood pressure. With a purity of 97.5%, this compound is significant in both clinical and research settings, particularly in studies related to neurotransmitter function and pharmacology. Its molecular weight is 608.70 g/mol, and it is classified under CAS No. 50-55-5, making it a well-defined chemical entity in the pharmaceutical industry.
Also known as Serpasil, Reserpin.
- Catalogue No.
- AL1287D
- CAS Number
- 50-55-5
- Molecular Formula
- C33H40N2O9
- Molecular Weight
- 608.70 g/mol
- HSN Code
- 29362990
- Grade
- 97.5%
- Product Form
- Substance
Reserpine appears as a white to pale yellow crystalline powder, which is light-sensitive and should be protected from exposure to light to maintain its stability. It is practically insoluble in water, which is a characteristic feature of many alkaloids, but it can dissolve in organic solvents such as ethanol and chloroform. The compound has a melting point of approximately 250°C, indicating its thermal stability. Its density is around 1.3 g/cm³, which is typical for crystalline organic compounds.
- Appearance
- White to pale yellow crystalline powder
- Shelf Life
- 2 years
- Packaging
- Available in 10 g and 100 g glass vials
- Storage
- Store at 2-8°C, protected from light and moisture.
1.1 — Product identifier
- Chemical Name
- Reserpine
- Catalogue No.
- AL1287D
- Product form
- Substance
- CAS Number
- 50-55-5
- EC Number
- 200-059-0
- Grade
- 97.5%
- EC Index Number
- None
- Chemical Formula
- C33H40N2O9
- HSN Code
- 29362990
- Synonyms
- Serpasil, Reserpin
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Pharmaceutical reference standard, research applications
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Light-sensitive, handle with care
3.1 — Substance
- Name
- Reserpine
- CAS No.
- 50-55-5
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Headache, dizziness, gastrointestinal disturbances, hypotension.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- May emit toxic fumes under fire conditions.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill, avoid dust generation, and ventilate area.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment and dispose of waste according to local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Handle with gloves and avoid exposure to light.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from light and moisture.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use in a well-ventilated area; use respiratory protection if necessary.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White to pale yellow
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 250°C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.3 g/cm³
- Solubility
- Practically insoluble in water, soluble in ethanol and chloroform
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under recommended storage conditions.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- LD50 (oral, rat) = 50 mg/kg.
- Skin corrosion/irritation
- May cause skin irritation.
- Serious eye damage/irritation
- May cause eye irritation.
- Respiratory or skin sensitisation
- Not a skin sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not classified as dangerous goods.
- UN-No. (IMDG)
- Not classified as dangerous goods.
- UN-No. (IATA)
- Not classified as dangerous goods.
- UN-No. (ADN)
- Not classified as dangerous goods.
- UN-No. (RID)
- Not classified as dangerous goods.
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Reserpine
- Proper Shipping Name (IMDG)
- Reserpine
- Proper Shipping Name (IATA)
- Reserpine
- Proper Shipping Name (ADN)
- Reserpine
- Proper Shipping Name (RID)
- Reserpine
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Reserpine is primarily used as a reference standard in pharmaceutical quality control laboratories, where it serves as a benchmark for the analysis of related compounds. Additionally, it is employed in neurotransmitter-depletion research, particularly in studies investigating the role of monoamines in mood disorders and hypertension. The compound has historical significance in the treatment of hypertension and is also studied for its potential effects on mental health conditions, such as schizophrenia and anxiety disorders. Its role in pharmacology extends to understanding the mechanisms of action of other psychotropic medications.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1287D
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 608.70 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 97.5% | 98.2% |
| Moisture Content | ≤ 1.0% | 0.5% |
| Residue on Ignition | ≤ 0.5% | 0.3% |
| Related Substances | None detected | None detected |
| Solubility | Practically insoluble in water | Practically insoluble in water |
The above product is expected to comply with 97.5% grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 97.5% | ≥ 97.5% | 250°C | ≤ 1.0% | ≤ 0.5% | None detected | Practically insoluble in water |
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