Sodium 1-propanesulfonate

For HPLC For Laboratory Use
CAS Number
14533-63-2
HSN Code
29041090
Molecular Formula
C3H7NaO3S
Catalogue Number
AL1269E
Purity
99%
Molecular Weight
146.14 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White crystalline powder
Shelf Life 2 years
Packaging Available in 100 g and 500 g bottles
Storage Store in a cool, dry place away from direct sunlight.

Sodium 1-propanesulfonate (for HPLC) is a small ion-pairing reagent that plays a crucial role in reversed-phase high-performance liquid chromatography (HPLC). This compound is particularly effective for the analysis of polar and ionic compounds, enhancing the separation and detection of these analytes in complex mixtures. With a high purity of 99%, it is specifically designed for HPLC applications, ensuring reliable and reproducible results. Its unique properties make it an essential tool in various analytical laboratories, particularly in pharmaceutical and biochemical research.

Also known as 1-Propanesulfonic acid, sodium salt.

Catalogue No.
AL1269E
CAS Number
14533-63-2
Molecular Formula
C3H7NaO3S
Molecular Weight
146.14 g/mol
HSN Code
29041090
Grade
For HPLC
Product Form
Substance

Sodium 1-propanesulfonate appears as a white crystalline powder. It is highly soluble in water, which facilitates its use in aqueous mobile phases for HPLC. The compound has a melting point of approximately 200 °C, and its density is around 1.1 g/cm³. The compound is stable under normal conditions and does not exhibit any significant odor, making it suitable for laboratory environments. Its solubility in water allows for easy preparation of solutions for analytical applications.

Appearance
White crystalline powder
Shelf Life
2 years
Packaging
Available in 100 g and 500 g bottles
Storage
Store in a cool, dry place away from direct sunlight.

1.1 — Product identifier

Chemical Name
Sodium 1-propanesulfonate
Catalogue No.
AL1269E
Product form
Substance
CAS Number
14533-63-2
EC Number
238-964-4
Grade
For HPLC
EC Index Number
Not applicable
Chemical Formula
C3H7NaO3S
HSN Code
29041090
Synonyms
1-Propanesulfonic acid, sodium salt

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Ion-pairing reagent in HPLC
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
None known

3.1 — Substance

Name
Sodium 1-propanesulfonate
CAS No.
14533-63-2

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
May cause mild irritation to skin and eyes.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Non-flammable; however, combustion may produce toxic fumes.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and collect using appropriate materials. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place. Keep container tightly closed.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Not required under normal conditions; use in well-ventilated areas.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White
Odour
Odourless
Odour threshold
Not applicable
pH value
7-9 (1% solution)
Relative evaporation rate (butylacetate=1)
Not applicable
Melting point
200 °C
Freezing point
Not applicable
Boiling point
Not applicable
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
Not applicable
Flammability (solid, gas)
Non-flammable
Vapour pressure
Not applicable
Relative vapour density at 20°C
Not applicable
Density
1.1 g/cm³
Solubility
Soluble in water
Log Pow
Not applicable
Viscosity, kinematic
Not applicable
Viscosity, dynamic
Not applicable
Explosive properties
Not applicable
Oxidising properties
Not applicable
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Stable under normal conditions.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizing agents.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Low toxicity; LD50 (oral, rat) > 2000 mg/kg.
Skin corrosion/irritation
May cause mild irritation.
Serious eye damage/irritation
May cause mild irritation.
Respiratory or skin sensitisation
Not a sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
Not classified as a specific target organ toxicant.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
Not applicable
UN-No. (IMDG)
Not applicable
UN-No. (IATA)
Not applicable
UN-No. (ADN)
Not applicable
UN-No. (RID)
Not applicable

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Not classified as dangerous goods
Proper Shipping Name (IMDG)
Not classified as dangerous goods
Proper Shipping Name (IATA)
Not classified as dangerous goods
Proper Shipping Name (ADN)
Not classified as dangerous goods
Proper Shipping Name (RID)
Not classified as dangerous goods

14.3 — Transport hazard class(es)

Transport hazard class(es)
Not applicable

14.4 — Packing group

Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Sodium 1-propanesulfonate is primarily used as an ion-pairing reagent in reversed-phase HPLC, where it aids in the separation of polar and ionic analytes. This makes it invaluable in the pharmaceutical industry for drug analysis and quality control, as well as in environmental testing for pollutants. Additionally, it is utilized in biochemical research for the analysis of biomolecules such as proteins and nucleic acids. Its effectiveness in enhancing chromatographic resolution makes it a preferred choice among chemists and researchers in various fields.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL1269E
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
146.14 g/mol
Test Standard Observed
Assay 99% min 99.5%
Moisture Content <1% 0.5%
Residue on Ignition <0.1% 0.05%
pH of 1% solution 7-9 7.5
Related Substances None detected None detected

The above product is expected to comply with For HPLC grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
For HPLC 99% 200 °C <1% <0.1% None detected Soluble in water
View full Technical Data Sheet

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