Sodium Cholate
- CAS Number
- 361-09-1
- HSN Code
- 29181990
- Molecular Formula
- C24H39NaO5
- Catalogue Number
- AL1367A
- Purity
- ≥ 98%
- Molecular Weight
- 430.56 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Sodium cholate (for biochemistry) is a soluble bile acid salt widely used as a detergent to solubilize membrane proteins. It is derived from the natural bile acids and is known for its ability to disrupt lipid bilayers, making it an essential reagent in biochemistry and molecular biology. This compound is particularly notable for its role in the study of membrane proteins, which are crucial for various biological functions. With a purity of 98%, it is suitable for high-quality research applications.
Also known as Sodium cholate, Sodium salt of cholanic acid.
- Catalogue No.
- AL1367A
- CAS Number
- 361-09-1
- Molecular Formula
- C24H39NaO5
- Molecular Weight
- 430.56 g/mol
- HSN Code
- 29181990
- Grade
- For Biochemistry
- Product Form
- Substance
Sodium cholate appears as a white to off-white powder. It is highly soluble in water, allowing for easy preparation of solutions for experimental use. The melting point of sodium cholate is approximately 200 °C, and it has a density of about 1.1 g/cm³. The compound has a characteristic odor, typical of bile salts, and is stable under normal laboratory conditions. Its solubility in water is a key property that facilitates its use in biochemical applications.
- Appearance
- White to off-white powder
- Shelf Life
- -
- Packaging
- -
- Storage
- Store in a cool, dry place, away from direct sunlight.
1.1 — Product identifier
- Chemical Name
- Sodium Cholate
- Catalogue No.
- AL1367A
- Product form
- Substance
- CAS Number
- 361-09-1
- EC Number
- 206-360-2
- Grade
- For Biochemistry
- EC Index Number
- Not specified
- Chemical Formula
- C24H39NaO5
- HSN Code
- 29181990
- Synonyms
- Sodium cholate, Sodium salt of cholanic acid
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used as a detergent in biochemical applications
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- None identified
3.1 — Substance
- Name
- Sodium Cholate
- CAS No.
- 361-09-1
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- May cause mild irritation to skin, eyes, and respiratory tract.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- No special hazards identified.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and collect using appropriate methods. Dispose of in accordance with local regulations.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment. Clean up spills immediately to prevent slipping hazards.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use in a well-ventilated area.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if dust is generated.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White to off-white
- Odour
- Characteristic of bile salts
- Odour threshold
- Not specified
- pH value
- Not specified
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- ~200 °C
- Freezing point
- Not specified
- Boiling point
- Not specified
- Flash point
- Not specified
- Auto-ignition temperature
- Not specified
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not specified
- Relative vapour density at 20°C
- Not specified
- Density
- ~1.1 g/cm³
- Solubility
- Soluble in water
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not specified
10.1 — Reactivity
- Reactivity
- Stable under normal conditions.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Not classified as acutely toxic.
- Skin corrosion/irritation
- May cause mild irritation.
- Serious eye damage/irritation
- May cause mild irritation.
- Respiratory or skin sensitisation
- Not classified as a sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- Not classified as a specific target organ toxicant.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- Not assigned
- UN-No. (IMDG)
- Not assigned
- UN-No. (IATA)
- Not assigned
- UN-No. (ADN)
- Not assigned
- UN-No. (RID)
- Not assigned
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Not classified as dangerous goods
- Proper Shipping Name (IMDG)
- Not classified as dangerous goods
- Proper Shipping Name (IATA)
- Not classified as dangerous goods
- Proper Shipping Name (ADN)
- Not classified as dangerous goods
- Proper Shipping Name (RID)
- Not classified as dangerous goods
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- Not applicable
14.4 — Packing group
- Packing group (ADR)
- Not applicable
- Packing group (IMDG)
- Not applicable
- Packing group (IATA)
- Not applicable
- Packing group (ADN)
- Not applicable
- Packing group (RID)
- Not applicable
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Sodium cholate is primarily used as a mild detergent to solubilize and stabilize membrane proteins in biochemistry and structural biology research. It is employed in various applications, including protein purification, crystallization, and the study of protein-lipid interactions. Additionally, sodium cholate is utilized in the preparation of liposomes and in the formulation of drug delivery systems. Its ability to enhance the solubility of hydrophobic compounds makes it valuable in pharmaceutical and biotechnological industries.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL1367A
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 430.56 g/mol
| Test | Standard | Observed |
|---|---|---|
| Description | White powder | White powder |
| Assay | 98 - 101% | 98.19% |
| Chloride (Cl) | <0.002% | <0.002% |
| Desoxychloric acid (TLC) | <0.5% | 0.4% |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For Biochemistry | ≥ 98% | ~200 °C | ≤ 1% | ≤ 0.5% | None detected | Soluble in water |
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