TES Buffer

For Molecular Biology For Laboratory Use
CAS Number
7365-44-8
HSN Code
29221990
Molecular Formula
C6H15NO6S
Catalogue Number
AL2562A
Purity
99%
Molecular Weight
229.25 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance White crystalline powder
Shelf Life 2 years
Packaging Available in 100 g and 500 g bottles
Storage Store in a cool, dry place, away from direct sunlight.

TES buffer (for molecular biology/biochemistry) is a widely used Good's biological buffer in the physiological pH range. It is particularly effective in maintaining stable pH levels in biological systems, making it essential for various laboratory applications. The buffer is known for its low ionic strength and minimal interference with biological reactions, which is crucial for accurate experimental results. With a purity of 99%, this reagent is suitable for sensitive applications in molecular biology and biochemistry, ensuring high-quality performance in research and development.

Also known as N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid.

Catalogue No.
AL2562A
CAS Number
7365-44-8
Molecular Formula
C6H15NO6S
Molecular Weight
229.25 g/mol
HSN Code
29221990
Grade
For Molecular Biology
Product Form
Substance

TES buffer appears as a white crystalline powder that is highly soluble in water, allowing for easy preparation of buffer solutions. It has a melting point of approximately 150 °C, and its solubility in water is around 50 g/L at room temperature. The buffer maintains a stable pH in the range of 6.8 to 8.2, making it ideal for various biological applications. The density of TES buffer is approximately 1.2 g/cm³, which is typical for crystalline organic compounds.

Appearance
White crystalline powder
Shelf Life
2 years
Packaging
Available in 100 g and 500 g bottles
Storage
Store in a cool, dry place, away from direct sunlight.

1.1 — Product identifier

Chemical Name
TES Buffer
Catalogue No.
AL2562A
Product form
Substance
CAS Number
7365-44-8
EC Number
230-785-7
Grade
For Molecular Biology
EC Index Number
Not applicable
Chemical Formula
C6H15NO6S
HSN Code
29221990
Synonyms
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Biological buffer for molecular biology and biochemistry applications
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
None identified

3.1 — Substance

Name
TES Buffer
CAS No.
7365-44-8

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
First-aid measures after ingestion
Rinse mouth. Do not induce vomiting. Seek medical attention if symptoms occur.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
May cause mild irritation to skin, eyes, and respiratory tract.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Non-flammable; however, use appropriate fire-fighting measures for surrounding materials.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and collect using appropriate protective equipment. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Use appropriate personal protective equipment. Sweep up and place in a suitable container for disposal.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Avoid contact with skin and eyes. Use in a well-ventilated area.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place, away from incompatible materials.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Not required under normal conditions of use; use in well-ventilated areas.

9.1 — Information on basic physical and chemical properties

Physical state
Solid
Colour
White
Odour
Odourless
Odour threshold
Not applicable
pH value
6.8 - 8.2 (in solution)
Relative evaporation rate (butylacetate=1)
Not applicable
Melting point
150 °C
Freezing point
Not applicable
Boiling point
Not applicable
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
Not applicable
Flammability (solid, gas)
Not flammable
Vapour pressure
Not applicable
Relative vapour density at 20°C
Not applicable
Density
1.2 g/cm³
Solubility
50 g/L in water
Log Pow
Not applicable
Viscosity, kinematic
Not applicable
Viscosity, dynamic
Not applicable
Explosive properties
Not explosive
Oxidising properties
Not oxidising
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Stable under normal conditions of use and storage.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong oxidizing agents.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Not classified as acutely toxic.
Skin corrosion/irritation
May cause mild irritation.
Serious eye damage/irritation
May cause mild irritation.
Respiratory or skin sensitisation
Not a sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
Not classified as a specific target organ toxicant.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
Not classified as dangerous goods.
UN-No. (IMDG)
Not classified as dangerous goods.
UN-No. (IATA)
Not classified as dangerous goods.
UN-No. (ADN)
Not classified as dangerous goods.
UN-No. (RID)
Not classified as dangerous goods.

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Not applicable
Proper Shipping Name (IMDG)
Not applicable
Proper Shipping Name (IATA)
Not applicable
Proper Shipping Name (ADN)
Not applicable
Proper Shipping Name (RID)
Not applicable

14.3 — Transport hazard class(es)

Transport hazard class(es)
Not applicable

14.4 — Packing group

Packing group (ADR)
Not applicable
Packing group (IMDG)
Not applicable
Packing group (IATA)
Not applicable
Packing group (ADN)
Not applicable
Packing group (RID)
Not applicable

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

TES buffer is widely used in molecular biology and biochemistry as a biological buffer to maintain pH stability in cell-culture media and enzymatic reactions. It is particularly useful in applications involving protein purification, enzyme assays, and nucleic acid studies. The buffer is also employed in various diagnostic and therapeutic procedures, including the preparation of samples for electrophoresis and chromatography. Its compatibility with a range of biological systems makes it a preferred choice in laboratories focused on cellular and molecular research.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL2562A
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
229.25 g/mol
Test Standard Observed
Assay Purity 99% min 99.5%
Moisture Content <1% 0.5%
Residue on Ignition <0.1% 0.05%
pH (1% solution) 6.8 - 8.2 7.0
Solubility 50 g/L in water 52 g/L in water

The above product is expected to comply with For Molecular Biology grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
For Molecular Biology 99% 150 °C <1% <0.1% None detected 50 g/L in water
View full Technical Data Sheet

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