Tetramethylammonium chloride
- CAS Number
- 75-57-0
- HSN Code
- 29239000
- Molecular Formula
- C4H12ClN
- Catalogue Number
- AL2567A
- Purity
- ≥ 98%
- Molecular Weight
- 109.61 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Tetramethylammonium chloride (TMAC) is a quaternary ammonium salt that serves as a versatile synthetic reagent in organic chemistry. It is characterized by its high purity of 98%, making it suitable for various synthesis applications. TMAC is notable for its role as a phase-transfer catalyst, facilitating the transfer of reactants between immiscible phases, which is crucial in many organic reactions. Its chemical structure, consisting of four methyl groups attached to a nitrogen atom, contributes to its solubility and reactivity in aqueous solutions.
Also known as TMAC, N,N,N-Trimethylmethanaminium chloride.
- Catalogue No.
- AL2567A
- CAS Number
- 75-57-0
- Molecular Formula
- C4H12ClN
- Molecular Weight
- 109.61 g/mol
- HSN Code
- 29239000
- Grade
- For Synthesis
- Product Form
- Substance
Tetramethylammonium chloride appears as a white crystalline powder. It has a melting point of approximately 240 °C and is highly soluble in water, with a solubility of around 1 g/mL at room temperature. The compound has a density of about 1.03 g/cm³. It is odorless and stable under normal conditions, but it should be stored in a cool, dry place to maintain its integrity. The compound is hygroscopic, meaning it can absorb moisture from the air, which may affect its performance in synthesis applications.
- Appearance
- White crystalline powder
- Shelf Life
- 2 years
- Packaging
- Available in 100 g and 500 g containers
- Storage
- Store in a cool, dry place, away from moisture and incompatible materials.
1.1 — Product identifier
- Chemical Name
- Tetramethylammonium chloride
- Catalogue No.
- AL2567A
- Product form
- Substance
- CAS Number
- 75-57-0
- EC Number
- 200-898-2
- Grade
- For Synthesis
- EC Index Number
- 615-001-00-8
- Chemical Formula
- C4H12ClN
- HSN Code
- 29239000
- Synonyms
- TMAC, N,N,N-Trimethylmethanaminium chloride
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Used as a phase-transfer catalyst and in organic synthesis.
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- May cause respiratory irritation; handle in a well-ventilated area.
3.1 — Substance
- Name
- Tetramethylammonium chloride
- CAS No.
- 75-57-0
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If symptoms persist, seek medical attention.
- First-aid measures after skin contact
- Wash with soap and water. If irritation occurs, seek medical attention.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. Seek medical attention if irritation persists.
- First-aid measures after ingestion
- Rinse mouth. Do not induce vomiting. Seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Symptoms of exposure may include irritation of the skin, eyes, and respiratory tract.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Toxic fumes may be released in a fire. Use appropriate fire-fighting measures.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Contain spill and prevent entry into waterways. Wear appropriate protective equipment.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Collect spillage and dispose of in accordance with local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Avoid contact with skin and eyes. Use personal protective equipment as required.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from incompatible materials such as strong oxidizers.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use appropriate respiratory protection if ventilation is inadequate.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Odourless
- Odour threshold
- Not applicable
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not applicable
- Melting point
- 240 °C
- Freezing point
- Not applicable
- Boiling point
- Not applicable
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not applicable
- Flammability (solid, gas)
- Not flammable
- Vapour pressure
- Not applicable
- Relative vapour density at 20°C
- Not applicable
- Density
- 1.03 g/cm³
- Solubility
- Soluble in water
- Log Pow
- Not applicable
- Viscosity, kinematic
- Not applicable
- Viscosity, dynamic
- Not applicable
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; avoid strong oxidizing agents.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong oxidizing agents, strong acids.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Toxic if swallowed or inhaled; LD50 (oral, rat) = 200-500 mg/kg.
- Skin corrosion/irritation
- Causes skin irritation.
- Serious eye damage/irritation
- Causes serious eye irritation.
- Respiratory or skin sensitisation
- Not a skin sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- UN 2811
- UN-No. (IMDG)
- UN 2811
- UN-No. (IATA)
- UN 2811
- UN-No. (ADN)
- UN 2811
- UN-No. (RID)
- UN 2811
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (IMDG)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (IATA)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (ADN)
- Toxic solid, organic, n.o.s.
- Proper Shipping Name (RID)
- Toxic solid, organic, n.o.s.
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- II
- Packing group (IMDG)
- II
- Packing group (IATA)
- II
- Packing group (ADN)
- II
- Packing group (RID)
- II
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Tetramethylammonium chloride is widely used in organic synthesis as a phase-transfer catalyst, which enhances the efficiency of reactions involving ionic compounds. It is particularly useful in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, TMAC serves as a reference compound in research studies involving quaternary ammonium salts, helping to elucidate reaction mechanisms and optimize synthetic pathways. Its ability to facilitate the transfer of reactants across phase boundaries makes it invaluable in both academic and industrial laboratories.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL2567A
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 109.61 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | 98 % min. | 98.23% |
The above product complies with LR grade
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| For Synthesis | ≥ 98% | 240 °C | ≤ 1% | ≤ 0.5% | None detected | Soluble in water |
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