Tetramethylammonium hydroxide

0.1N solution in 2-propanol For Laboratory Use
CAS Number
-
HSN Code
38229090
Molecular Formula
C4H11NO
Catalogue Number
AL2572C
Purity
0.1N
Molecular Weight
91.15 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance Clear, colorless liquid
Shelf Life 12 months
Packaging Available in 500 mL and 1 L bottles
Storage Store in a cool, dry place away from heat sources and incompatible materials.

Tetramethylammonium hydroxide 0.1N solution in 2-propanol is a standardized preparation for non-aqueous titration applications. This solution is particularly useful in analytical chemistry for titrating weak acids and bases, providing a reliable means of determining concentrations in non-aqueous environments. The tetramethylammonium ion acts as a strong base, making it suitable for various titrations where water is not the solvent of choice. Its formulation in 2-propanol enhances its solubility and stability, making it a preferred choice for laboratory settings.

Also known as Tetramethylammonium hydroxide solution.

Catalogue No.
AL2572C
CAS Number
-
Molecular Formula
C4H11NO
Molecular Weight
91.15 g/mol
HSN Code
38229090
Grade
0.1N solution in 2-propanol
Product Form
Mixture

The product appears as a clear, colorless liquid, indicative of its purity and lack of impurities. It has a density of approximately 0.785 g/cm³ at 20°C, which is typical for solutions containing 2-propanol. The boiling point of the solution is around 82.5°C, while the flash point is approximately 12°C, highlighting its flammable nature. Tetramethylammonium hydroxide is soluble in polar solvents, and in this case, it is fully miscible with 2-propanol, allowing for effective titration applications.

Appearance
Clear, colorless liquid
Shelf Life
12 months
Packaging
Available in 500 mL and 1 L bottles
Storage
Store in a cool, dry place away from heat sources and incompatible materials.

1.1 — Product identifier

Chemical Name
Tetramethylammonium hydroxide
Catalogue No.
AL2572C
Product form
Mixture
CAS Number
Not applicable
EC Number
200-898-2
Grade
0.1N solution in 2-propanol
EC Index Number
Not applicable
Chemical Formula
C4H11NO
HSN Code
38229090
Synonyms
Tetramethylammonium hydroxide solution

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used as a base titrant in non-aqueous titration applications
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
Corrosive to metals; may cause skin and eye irritation.

3.1 — Substance

Name
Tetramethylammonium hydroxide
CAS No.
Not applicable

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with soap and water. If irritation occurs, seek medical attention.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and seek medical attention.
First-aid measures after ingestion
Do not induce vomiting. Rinse mouth and seek medical attention immediately.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
Irritation of the respiratory tract, skin, and eyes; potential burns on contact.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Flammable liquid; vapors may form explosive mixtures with air.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Evacuate area and ventilate. Contain spill and absorb with inert material.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Collect and dispose of in accordance with local regulations.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Use personal protective equipment (PPE) such as gloves and goggles. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in tightly closed containers in a cool, dry place away from incompatible materials.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use appropriate respiratory protection if ventilation is inadequate.

9.1 — Information on basic physical and chemical properties

Physical state
Liquid
Colour
Colorless
Odour
Characteristic odor of isopropanol
Odour threshold
Not determined
pH value
Alkaline
Relative evaporation rate (butylacetate=1)
Not determined
Melting point
Not applicable
Freezing point
Not applicable
Boiling point
82.5°C
Flash point
12°C
Auto-ignition temperature
Not determined
Decomposition temperature
Not determined
Flammability (solid, gas)
Flammable liquid
Vapour pressure
Not determined
Relative vapour density at 20°C
Not determined
Density
0.785 g/cm³
Solubility
Fully miscible in water and 2-propanol
Log Pow
Not determined
Viscosity, kinematic
Not determined
Viscosity, dynamic
Not determined
Explosive properties
Not explosive
Oxidising properties
Not oxidizing
Explosive limits
Not determined

10.1 — Reactivity

Reactivity
Stable under normal conditions; reacts with strong acids.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong acids, strong oxidizers, and moisture.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
May cause irritation; no significant acute toxicity data available.
Skin corrosion/irritation
Causes skin irritation.
Serious eye damage/irritation
Causes serious eye irritation.
Respiratory or skin sensitisation
Not expected to be a skin sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
Not classified as a specific target organ toxicant.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
UN 3267
UN-No. (IMDG)
UN 3267
UN-No. (IATA)
UN 3267
UN-No. (ADN)
UN 3267
UN-No. (RID)
UN 3267

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Corrosive liquid, basic, organic, n.o.s. (Tetramethylammonium hydroxide solution)
Proper Shipping Name (IMDG)
Corrosive liquid, basic, organic, n.o.s. (Tetramethylammonium hydroxide solution)
Proper Shipping Name (IATA)
Corrosive liquid, basic, organic, n.o.s. (Tetramethylammonium hydroxide solution)
Proper Shipping Name (ADN)
Corrosive liquid, basic, organic, n.o.s. (Tetramethylammonium hydroxide solution)
Proper Shipping Name (RID)
Corrosive liquid, basic, organic, n.o.s. (Tetramethylammonium hydroxide solution)

14.3 — Transport hazard class(es)

Transport hazard class(es)
8

14.4 — Packing group

Packing group (ADR)
II
Packing group (IMDG)
II
Packing group (IATA)
II
Packing group (ADN)
II
Packing group (RID)
II

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Tetramethylammonium hydroxide 0.1N solution in 2-propanol is primarily used as a standardized base titrant in non-aqueous acid-base titration research. It is widely utilized in the pharmaceutical industry for the analysis of drug formulations, as well as in academic laboratories for educational purposes in analytical chemistry courses. Additionally, it finds applications in the synthesis of various organic compounds where precise pH control is necessary. Its use extends to the production of surfactants and in the study of reaction kinetics in non-aqueous media.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL2572C
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
91.15 g/mol
Test Standard Observed
Assay 0.1N 0.1N
Appearance Clear, colorless liquid Clear, colorless liquid
Density 0.785 g/cm³ 0.785 g/cm³
Boiling Point 82.5°C 82.5°C

The above product is expected to comply with 0.1N solution in 2-propanol grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
0.1N solution in 2-propanol 0.1N 82.5°C Not specified Not specified Not specified Fully miscible in water and 2-propanol
View full Technical Data Sheet

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