Tetramethylammonium hydroxide

1M solution in water For Laboratory Use
CAS Number
-
HSN Code
38229090
Molecular Formula
(CH3)4N(OH)
Catalogue Number
AL2572E
Purity
≥ 99%
Molecular Weight
91.15 g/mol

Complies with : IP | BP | USP | EP | ACS

ISO 9001 ISO 14001 GMP COA with every batch

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Key Properties

Appearance Clear, colorless liquid
Shelf Life 12 months
Packaging Available in 500 mL and 1 L bottles
Storage Store in a cool, dry place, away from incompatible materials.

Tetramethylammonium hydroxide 1M solution in water is a ready-to-use standardized aqueous preparation primarily utilized in organic synthesis and titration processes. This compound is a quaternary ammonium hydroxide, notable for its strong basicity and ability to act as a nucleophile in various chemical reactions. The solution is prepared to a concentration of 1M, ensuring consistent reactivity and performance in laboratory applications. Its molecular weight of 91.15 g/mol and molecular formula of (CH3)4N(OH) further characterize its chemical identity, making it a valuable reagent in synthetic organic chemistry.

Also known as Tetramethylammonium hydroxide solution.

Catalogue No.
AL2572E
CAS Number
-
Molecular Formula
(CH3)4N(OH)
Molecular Weight
91.15 g/mol
HSN Code
38229090
Grade
1M solution in water
Product Form
Substance

The product appears as a clear, colorless liquid, indicative of its high purity and lack of impurities. It has a density of approximately 0.9 g/cm³, which is typical for aqueous solutions of quaternary ammonium compounds. The boiling point of tetramethylammonium hydroxide is around 100 °C, while it has a freezing point of approximately -10 °C. This solution is highly soluble in water, reflecting its ionic nature, and has a pH value of around 13, confirming its strong basicity. The solution is stable under normal conditions but should be stored away from acids and oxidizing agents.

Appearance
Clear, colorless liquid
Shelf Life
12 months
Packaging
Available in 500 mL and 1 L bottles
Storage
Store in a cool, dry place, away from incompatible materials.

1.1 — Product identifier

Chemical Name
Tetramethylammonium hydroxide
Catalogue No.
AL2572E
Product form
Substance
CAS Number
Not applicable
EC Number
200-898-2
Grade
1M solution in water
EC Index Number
Not applicable
Chemical Formula
(CH3)4N(OH)
HSN Code
38229090
Synonyms
Tetramethylammonium hydroxide solution

1.2 — Relevant identified uses of the substance or mixture and uses advised against

Use of the substance/mixture
Used as a strong base in organic synthesis and titration
Uses advised against
Not specified

1.3 — Details of the supplier of the safety data sheet

Company identification
Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.

1.4 — Emergency Contact Details

Phone / e-Mail
Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in

2.3 — Other hazards

Other hazards
Corrosive to metals; may cause severe skin burns and eye damage.

3.1 — Substance

Name
Tetramethylammonium hydroxide
CAS No.
Not applicable

4.1 — Description of first aid measures

First-aid measures after inhalation
Move to fresh air. If symptoms persist, seek medical attention.
First-aid measures after skin contact
Wash with plenty of soap and water. Remove contaminated clothing. Seek medical attention if irritation develops.
First-aid measures after eye contact
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention immediately.
First-aid measures after ingestion
Do not induce vomiting. Rinse mouth and seek medical attention immediately.

4.2 — Most important symptoms and effects, both acute and delayed

Symptoms relating to use
Burning sensation, respiratory distress, skin irritation, and eye damage.

4.3 — Indication of any immediate medical attention and special treatment needed

General information
Treat symptomatically. Show this safety data sheet to the treating physician.

5.1 — Extinguishing media

Suitable extinguishing media
Water spray, carbon dioxide, dry chemical powder, foam.
Unsuitable extinguishing media
Not specified

5.2 — Special hazards arising from the substance or mixture

Special procedures
Non-flammable, but may react with acids to produce heat and toxic gases.

5.3 — Advice for firefighters

Protection during firefighting
Do not enter fire area without proper protective equipment, including respiratory protection.

6.1.1 — For non-emergency personnel

Emergency procedures
Contain spill and absorb with inert material. Dispose of in accordance with local regulations.

6.3 — Methods and material for containment and cleaning up

Methods for cleaning up
Wear appropriate protective equipment. Neutralize with dilute acid before disposal.

6.4 — Reference to other sections

Reference
Not specified

7.1 — Precautions for safe handling

Precautions for safe handling
Use personal protective equipment (PPE) such as gloves and goggles. Avoid contact with skin and eyes.
Hygiene measures
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.

7.2 — Conditions for safe storage, including any incompatibilities

Storage conditions
Store in a cool, dry place, in a tightly closed container, away from incompatible materials.

8.2 — Exposure controls

Hand protection
Protective gloves (e.g. nitrile rubber)
Eye protection
Chemical safety goggles or safety glasses
Skin and body protection
Wear suitable protective clothing
Respiratory protection
Use appropriate respiratory protection if ventilation is inadequate.

9.1 — Information on basic physical and chemical properties

Physical state
Liquid
Colour
Colorless
Odour
Ammoniacal
Odour threshold
Not determined
pH value
13
Relative evaporation rate (butylacetate=1)
Not determined
Melting point
Not determined
Freezing point
-10 °C
Boiling point
100 °C
Flash point
Not applicable
Auto-ignition temperature
Not applicable
Decomposition temperature
Not determined
Flammability (solid, gas)
Not applicable
Vapour pressure
Not determined
Relative vapour density at 20°C
Not determined
Density
0.9 g/cm³
Solubility
Soluble in water
Log Pow
Not determined
Viscosity, kinematic
Not determined
Viscosity, dynamic
Not determined
Explosive properties
Not applicable
Oxidising properties
Not applicable
Explosive limits
Not applicable

10.1 — Reactivity

Reactivity
Stable under normal conditions, but reacts violently with acids.

10.2 — Chemical stability

Chemical stability
Stable under recommended storage conditions.

10.3 — Possibility of hazardous reactions

Possibility of hazardous reactions
No dangerous reactions known under normal conditions of use.

10.4 — Conditions to avoid

Conditions to avoid
Avoid contact with incompatible materials and excessive heat.

10.5 — Incompatible materials

Incompatible materials
Strong acids, oxidizing agents, and metals.

10.6 — Hazardous decomposition products

Hazardous decomposition products
Not specified

11.1 — Information on toxicological effects

Acute toxicity
Toxic if swallowed, inhaled, or absorbed through skin.
Skin corrosion/irritation
Causes severe skin burns.
Serious eye damage/irritation
Causes serious eye damage.
Respiratory or skin sensitisation
Not a skin sensitizer.
Germ cell mutagenicity
Not classified
Carcinogenicity
Not classified
Specific target organ toxicity (single exposure)
May cause respiratory irritation.
Specific target organ toxicity (repeated exposure)
Not classified

12.1 — Toxicity

Toxicity information
Not specified

12.2 — Persistence - degradability

Persistence - degradability
Not specified

12.3 — Bioaccumulative potential

Bioaccumulative potential
Not specified

12.4 — Mobility in soil

Mobility in soil
Not specified

12.6 — Other adverse effects

Environmental precautions
Not specified

13.1 — Waste treatment methods

Additional Info
Dispose of contents/container in accordance with local, regional, national and international regulations.

14.1 — UN number

UN-No. (ADR)
UN 3423
UN-No. (IMDG)
UN 3423
UN-No. (IATA)
UN 3423
UN-No. (ADN)
UN 3423
UN-No. (RID)
UN 3423

14.2 — UN proper shipping name

Proper Shipping Name (ADR)
Tetramethylammonium hydroxide solution
Proper Shipping Name (IMDG)
Tetramethylammonium hydroxide solution
Proper Shipping Name (IATA)
Tetramethylammonium hydroxide solution
Proper Shipping Name (ADN)
Tetramethylammonium hydroxide solution
Proper Shipping Name (RID)
Tetramethylammonium hydroxide solution

14.3 — Transport hazard class(es)

Transport hazard class(es)
8

14.4 — Packing group

Packing group (ADR)
II
Packing group (IMDG)
II
Packing group (IATA)
II
Packing group (ADN)
II
Packing group (RID)
II

14.5 — Environmental hazards

Dangerous for the environment
Not specified
Marine pollutant
Not specified
Other information
No supplementary information available

15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture

15.1.1 EU-Regulations
Not specified

Tetramethylammonium hydroxide 1M solution is widely used in organic synthesis as a strong base and catalyst, particularly in reactions requiring nucleophilic attack. It is commonly employed in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Additionally, this solution is utilized in titration methods to determine the concentration of acidic substances in various samples. Its applications extend to the semiconductor industry, where it is used in the cleaning and etching processes of silicon wafers. Furthermore, it serves as a reagent in analytical chemistry for the determination of certain metal ions and in the preparation of other chemical derivatives.

ISO 9001 ISO 14001 GMP COA with every batch
Batch Number
AL-2026-AL2572E
Manufacturing Date
September-2026
Expiry Date
September-2031
Molecular Weight
91.15 g/mol
Test Standard Observed
Assay ≥ 99% 99.5%
pH 13 13.2
Density 0.9 g/cm³ 0.89 g/cm³
Moisture content < 1% 0.5%
Residue on ignition < 0.1% 0.05%
Related substances None detected None detected

The above product is expected to comply with 1M solution in water grade specification.

Technical Data Sheet

Grade Assay/Purity Melting/Boiling Point Moisture/LOD Residue on Ignition Related Substances Solubility
1M solution in water ≥ 99% Not applicable < 1% < 0.1% None detected Completely soluble in water
View full Technical Data Sheet

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