Triphosgene
- CAS Number
- 32315-10-9
- HSN Code
- 29209000
- Molecular Formula
- Cl3COCOOCCl3
- Catalogue Number
- AL2584D
- Purity
- ≥ 98%
- Molecular Weight
- 296.75 g/mol
Complies with : IP | BP | USP | EP | ACS
ISO 9001
ISO 14001
GMP
COA with every batch
Key Properties
Triphosgene (for synthesis) is a solid, safer-to-handle substitute for phosgene gas, widely used in organic synthesis for introducing carbonyl groups. It is particularly valued in the chemical industry for its ability to provide a controlled release of phosgene, which is a highly toxic gas. Triphosgene is a white crystalline solid that is stable under normal conditions but must be handled with care due to its potential to release phosgene upon decomposition. This compound is essential in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, making it a critical reagent in modern organic chemistry.
Also known as Trichloroformyl carbonate.
- Catalogue No.
- AL2584D
- CAS Number
- 32315-10-9
- Molecular Formula
- Cl3COCOOCCl3
- Molecular Weight
- 296.75 g/mol
- HSN Code
- 29209000
- Grade
- 98%
- Product Form
- Substance
Triphosgene appears as a white crystalline solid with a pungent odor reminiscent of phosgene. It has a melting point of approximately 50-52 °C and a boiling point of around 130 °C. The density of triphosgene is about 1.5 g/cm³, and it is soluble in organic solvents such as dichloromethane and acetone, but insoluble in water. The compound is stable under normal conditions but should be stored in a cool, dry place away from moisture and incompatible materials.
- Appearance
- White crystalline solid
- Shelf Life
- 2 years
- Packaging
- Available in 100 g and 500 g glass bottles
- Storage
- Store in a cool, dry place, away from moisture and incompatible materials.
1.1 — Product identifier
- Chemical Name
- Triphosgene
- Catalogue No.
- AL2584D
- Product form
- Substance
- CAS Number
- 32315-10-9
- EC Number
- 250-001-0
- Grade
- 98%
- EC Index Number
- 615-001-00-0
- Chemical Formula
- Cl3COCOOCCl3
- HSN Code
- 29209000
- Synonyms
- Trichloroformyl carbonate
1.2 — Relevant identified uses of the substance or mixture and uses advised against
- Use of the substance/mixture
- Intermediate in organic synthesis, phosgene substitute
- Uses advised against
- Not specified
1.3 — Details of the supplier of the safety data sheet
- Company identification
- Address:- 102, B wing, Savgan Heights, RTO Lane,Andheri (W), Mumbai-400 053Maharashtra, India.
1.4 — Emergency Contact Details
- Phone / e-Mail
- Phone : +91 22 26317055 Mobile : +91 9820385757 e-mail : info@alphachemika.co.in
2.3 — Other hazards
- Other hazards
- Releases phosgene gas upon decomposition; highly toxic and corrosive.
3.1 — Substance
- Name
- Triphosgene
- CAS No.
- 32315-10-9
4.1 — Description of first aid measures
- First-aid measures after inhalation
- Move to fresh air. If breathing is difficult, give oxygen. Seek medical attention immediately.
- First-aid measures after skin contact
- Remove contaminated clothing and wash skin thoroughly with soap and water. Seek medical attention if irritation persists.
- First-aid measures after eye contact
- Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and seek medical attention.
- First-aid measures after ingestion
- Do not induce vomiting. Rinse mouth and seek medical attention immediately.
4.2 — Most important symptoms and effects, both acute and delayed
- Symptoms relating to use
- Symptoms of exposure may include coughing, shortness of breath, skin irritation, and eye irritation.
4.3 — Indication of any immediate medical attention and special treatment needed
- General information
- Treat symptomatically. Show this safety data sheet to the treating physician.
5.1 — Extinguishing media
- Suitable extinguishing media
- Water spray, carbon dioxide, dry chemical powder, foam.
- Unsuitable extinguishing media
- Not specified
5.2 — Special hazards arising from the substance or mixture
- Special procedures
- Highly toxic fumes may be released in a fire; use appropriate fire-fighting measures.
5.3 — Advice for firefighters
- Protection during firefighting
- Do not enter fire area without proper protective equipment, including respiratory protection.
6.1.1 — For non-emergency personnel
- Emergency procedures
- Evacuate area and ventilate. Wear appropriate protective equipment. Contain and collect spillage.
6.3 — Methods and material for containment and cleaning up
- Methods for cleaning up
- Use appropriate personal protective equipment. Absorb with inert material and dispose of according to local regulations.
6.4 — Reference to other sections
- Reference
- Not specified
7.1 — Precautions for safe handling
- Precautions for safe handling
- Handle under a fume hood with appropriate PPE including gloves and goggles. Avoid inhalation and contact with skin.
- Hygiene measures
- Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2 — Conditions for safe storage, including any incompatibilities
- Storage conditions
- Store in a cool, dry place, away from moisture and incompatible materials such as strong bases and oxidizers.
8.2 — Exposure controls
- Hand protection
- Protective gloves (e.g. nitrile rubber)
- Eye protection
- Chemical safety goggles or safety glasses
- Skin and body protection
- Wear suitable protective clothing
- Respiratory protection
- Use a NIOSH-approved respirator if exposure limits are exceeded or if irritation occurs.
9.1 — Information on basic physical and chemical properties
- Physical state
- Solid
- Colour
- White
- Odour
- Pungent
- Odour threshold
- Not specified
- pH value
- Not applicable
- Relative evaporation rate (butylacetate=1)
- Not specified
- Melting point
- 50-52 °C
- Freezing point
- Not specified
- Boiling point
- 130 °C
- Flash point
- Not applicable
- Auto-ignition temperature
- Not applicable
- Decomposition temperature
- Not specified
- Flammability (solid, gas)
- Not flammable under normal conditions
- Vapour pressure
- Not specified
- Relative vapour density at 20°C
- Not specified
- Density
- 1.5 g/cm³
- Solubility
- Soluble in organic solvents, insoluble in water
- Log Pow
- Not specified
- Viscosity, kinematic
- Not specified
- Viscosity, dynamic
- Not specified
- Explosive properties
- Not explosive
- Oxidising properties
- Not oxidizing
- Explosive limits
- Not applicable
10.1 — Reactivity
- Reactivity
- Stable under normal conditions; decomposes to release phosgene gas when exposed to moisture or heat.
10.2 — Chemical stability
- Chemical stability
- Stable under recommended storage conditions.
10.3 — Possibility of hazardous reactions
- Possibility of hazardous reactions
- No dangerous reactions known under normal conditions of use.
10.4 — Conditions to avoid
- Conditions to avoid
- Avoid contact with incompatible materials and excessive heat.
10.5 — Incompatible materials
- Incompatible materials
- Strong bases, strong oxidizers, and moisture.
10.6 — Hazardous decomposition products
- Hazardous decomposition products
- Not specified
11.1 — Information on toxicological effects
- Acute toxicity
- Highly toxic; LD50 (oral, rat) is approximately 50 mg/kg.
- Skin corrosion/irritation
- Causes skin irritation.
- Serious eye damage/irritation
- Causes serious eye irritation.
- Respiratory or skin sensitisation
- Not a skin sensitizer.
- Germ cell mutagenicity
- Not classified
- Carcinogenicity
- Not classified
- Specific target organ toxicity (single exposure)
- May cause respiratory irritation.
- Specific target organ toxicity (repeated exposure)
- Not classified
12.1 — Toxicity
- Toxicity information
- Not specified
12.2 — Persistence - degradability
- Persistence - degradability
- Not specified
12.3 — Bioaccumulative potential
- Bioaccumulative potential
- Not specified
12.4 — Mobility in soil
- Mobility in soil
- Not specified
12.6 — Other adverse effects
- Environmental precautions
- Not specified
13.1 — Waste treatment methods
- Additional Info
- Dispose of contents/container in accordance with local, regional, national and international regulations.
14.1 — UN number
- UN-No. (ADR)
- 2928
- UN-No. (IMDG)
- 2928
- UN-No. (IATA)
- 2928
- UN-No. (ADN)
- 2928
- UN-No. (RID)
- 2928
14.2 — UN proper shipping name
- Proper Shipping Name (ADR)
- Triphosgene
- Proper Shipping Name (IMDG)
- Triphosgene
- Proper Shipping Name (IATA)
- Triphosgene
- Proper Shipping Name (ADN)
- Triphosgene
- Proper Shipping Name (RID)
- Triphosgene
14.3 — Transport hazard class(es)
- Transport hazard class(es)
- 6.1
14.4 — Packing group
- Packing group (ADR)
- I
- Packing group (IMDG)
- I
- Packing group (IATA)
- I
- Packing group (ADN)
- I
- Packing group (RID)
- I
14.5 — Environmental hazards
- Dangerous for the environment
- Not specified
- Marine pollutant
- Not specified
- Other information
- No supplementary information available
15.1 — Safety, health and environmental regulations/legislation specific for the substance or mixture
- 15.1.1 EU-Regulations
- Not specified
Triphosgene is primarily used as a solid phosgene equivalent in the synthesis of carbamates and isocyanates, which are important intermediates in the production of pesticides, herbicides, and pharmaceuticals. It is also utilized in the preparation of various organic compounds where controlled carbonyl group introduction is required. The compound is essential in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and in research laboratories for developing new chemical processes. Due to its hazardous nature, it is handled with strict phosgene-hazard precautions, typically in fume hoods with appropriate personal protective equipment.
ISO 9001
ISO 14001
GMP
COA with every batch
- Batch Number
- AL-2026-AL2584D
- Manufacturing Date
- September-2026
- Expiry Date
- September-2031
- Molecular Weight
- 296.75 g/mol
| Test | Standard | Observed |
|---|---|---|
| Assay | ≥ 98% | 99.5% |
| Melting Point | 50-52 °C | 51 °C |
| Moisture Content | ≤ 0.5% | 0.3% |
| Residue on Ignition | ≤ 0.1% | 0.05% |
| Related Substances | None detected | None detected |
| Solubility | Soluble in organic solvents | Soluble in dichloromethane and acetone. |
The above product is expected to comply with 98% grade specification.
Technical Data Sheet
| Grade | Assay/Purity | Melting/Boiling Point | Moisture/LOD | Residue on Ignition | Related Substances | Solubility |
|---|---|---|---|---|---|---|
| 98% | ≥ 98% | 50-52 °C / 130 °C | ≤ 0.5% | ≤ 0.1% | None detected | Soluble in organic solvents |
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